Edaravone (MCI-186), antioxidant (ab120645)
Key features and details
- Free radical scavenger with neuroprotective effects
- CAS Number: 89-25-8
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
-
製品名
Edaravone (MCI-186), antioxidant -
製品の詳細
Free radical scavenger with neuroprotective effects -
別名
- MCI-186
-
生理活性の詳細
Free radical scavenger and potent antioxidant. Inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system.
-
精製度
> 99% -
CAS 番号
89-25-8 -
構造式
製品の特性
-
体系名
3-Methyl-1-phenyl-2-pyrazolin-5-one -
分子量
174.20 -
分子式
C10H10N2O -
PubChem 登録番号
4021 -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES 線形表記
CC1=NN(C(=O)C1)C2=CC=CC=C2 -
由来
Synthetic
-
研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (3)
ab120645 は 3 報の論文で使用されています。
- Oh SJ et al. Ultrasonic Neuromodulation via Astrocytic TRPA1. Curr Biol 29:3386-3401.e8 (2019). PubMed: 31588000
- Cao A et al. Ursodeoxycholic Acid Ameliorated Diabetic Nephropathy by Attenuating Hyperglycemia-Mediated Oxidative Stress. Biol Pharm Bull 39:1300-8 (2016). PubMed: 27193377
- Jami MS et al. Edaravone leads to proteome changes indicative of neuronal cell protection in response to oxidative stress. Neurochem Int 90:134-41 (2015). PubMed: 26232623