Anti-EBNA 3A 抗体 (ab16126)
Key features and details
- Sheep polyclonal to EBNA 3A
- Suitable for: ICC, Dot blot, ELISA, IHC-Fr, WB
- Reacts with: Species independent
- Isotype: IgG
製品の概要
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製品名
Anti-EBNA 3A antibody -
製品の詳細
Sheep polyclonal to EBNA 3A -
由来種
Sheep -
特異性
This antibody is specific for the Epstein Barr Virus Nuclear Antigen 3A. -
アプリケーション
適用あり: ICC, Dot blot, ELISA, IHC-Fr, WBmore details -
種交差性
交差種: Species independent -
免疫原
Recombinant full length protein. Recombinant EBNA-3A protein
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特記事項
Sheep were immunized with recombinant EBNA-3A protein
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Ammonium Sulphate Precipitation -
特記事項（精製）
Purified by ammonium sulfate precipitation. This antibody is provided as a 0.2µm sterile filtered solution. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab16126の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC |
Use at an assay dependent concentration.
|
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| Dot blot |
Use at an assay dependent concentration.
|
|
| ELISA |
Use at an assay dependent concentration.
|
|
| IHC-Fr |
Use at an assay dependent concentration.
|
|
| WB | (1) |
Use a concentration of 0.25 - 1 µg/ml.
|
| 特記事項 |
|---|
|
ICC
Use at an assay dependent concentration. |
|
Dot blot
Use at an assay dependent concentration. |
|
ELISA
Use at an assay dependent concentration. |
|
IHC-Fr
Use at an assay dependent concentration. |
|
WB
Use a concentration of 0.25 - 1 µg/ml. |
ターゲット情報
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関連性
EBNA3A is a latent viral nuclear protein expressed in Epstein Barr Virus (EBV) transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA3A functions as a transcriptional regulator though the target genes are currently unknown. -
別名
- EBNA 3A antibody
- EBV antibody
- Epstein Barr virus antibody
see all
画像
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Western blot - Anti-EBNA 3A antibody (ab16126)All lanes : Anti-EBNA 3A antibody (ab16126)
All lanes : Cell line infected with Epstein Barr virus.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (11)
ab16126 は 11 報の論文で使用されています。
- Gain C et al. Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway. PLoS Pathog 16:e1008105 (2020). PubMed: 32092124
- Barzyk GA & Sheriff V EBV Positivity and Programmed Death-ligand 1 Expression in Diffuse Large B-cell Lymphoma: A Systematic Review. Anticancer Res 40:5951-5968 (2020). PubMed: 33109533
- Paschos K et al. Requirement for PRC1 subunit BMI1 in host gene activation by Epstein-Barr virus protein EBNA3C. Nucleic Acids Res N/A:N/A (2019). PubMed: 30649516
- Gillman ACT et al. Epstein-Barr Virus Nuclear Antigen 3C Inhibits Expression of COBLL1 and the ADAM28-ADAMDEC1 Locus via Interaction with the Histone Lysine Demethylase KDM2B. J Virol 92:N/A (2018). PubMed: 30135119
- Szymula A et al. Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome. PLoS Pathog 14:e1006890 (2018). PubMed: 29462212
