Anti-DUSP7 抗体 (ab95960)
Key features and details
- Rabbit polyclonal to DUSP7
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-DUSP7 antibody
DUSP7 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to DUSP7 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-P, ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Synthetic peptide with a sequence corresponding to a region within amino acids 258 and 320 of Human DUSP7 (NP_001938)
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ポジティブ・コントロール
- 293T, H1299, HepG2, Molt-4 and Raji cell lines.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95960の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 41 kDa.
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IHC-P |
1/100 - 1/500.
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ICC/IF |
1/100 - 1/200.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 41 kDa. |
IHC-P
1/100 - 1/500. |
ICC/IF
1/100 - 1/200. |
ターゲット情報
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機能
Regulates the activity of the MAP kinase family in response to changes in the cellular environment. PYST2-S may act as a negative regulator of PYST2-L although it is unclear whether this is by competing for transcription, translation or activation factors. -
組織特異性
Expressed at significantly higher levels in malignant hematopoietic cells than in corresponding non-malignant cells. -
配列類似性
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain.
Contains 1 tyrosine-protein phosphatase domain. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 1849 Human
- Entrez Gene: 235584 Mouse
- Omim: 602749 Human
- SwissProt: Q16829 Human
- SwissProt: Q91Z46 Mouse
- Unigene: 591664 Human
- Unigene: 275584 Mouse
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別名
- Dual specificity phosphatase 7 antibody
- Dual specificity protein phosphatase 7 antibody
- Dual specificity protein phosphatase PYST2 antibody
see all
画像
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Anti-DUSP7 antibody (ab95960) at 1/1000 dilution + Raji whole cell lysate at 30 µg
Predicted band size: 41 kDa
10% SDS PAGE -
ab95960, at 1/200, staining paraformaldehyde-fixed A549 cells by Immunofluorescence. Lower image merged with DNA probe.
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ab95960, at 1/100, staining paraffin-embedded NCIN87 xenograft, by Immunohistochemistry.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab95960 は 2 報の論文で使用されています。
- Wu L et al. Targeting DUSP7 signaling alleviates hepatic steatosis, inflammation and oxidative stress in high fat diet (HFD)-fed mice via suppression of TAK1. Free Radic Biol Med 153:140-158 (2020). PubMed: 32311490
- Yang W et al. Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis. Cancer Manag Res 12:2327-2337 (2020). PubMed: 32273769