Anti-DRD4 抗体 (ab20424)
Key features and details
- Rabbit polyclonal to DRD4
- Suitable for: ICC, ICC/IF, IHC-P, WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-DRD4 antibody
DRD4 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to DRD4 -
由来種
Rabbit -
特異性
Cross-reactivity: D4 Dopamine Receptor (176-185) 100% D4 Dopamine Receptor 60% D1 Dopamine Receptor (9-21) 0% D1 Dopamine Receptor 0% D2 Dopamine Receptor (272-282) 0% D2 Dopamine Receptor 0% D3 Dopamine Receptor (2-10) 0% D3 Dopamine Receptor 0% D5 Dopamine Receptor (23-35) 0% D5 Dopamine Receptor 0% -
アプリケーション
適用あり: ICC, ICC/IF, IHC-P, WBmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide corresponding to Human DRD4 aa 176-185 (N terminal).
Sequence:DVRGRDPAVC
(Peptide available asab49539) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Lyophilized antisera. -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab20424の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC |
Use at an assay dependent concentration.
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| ICC/IF |
Use at an assay dependent concentration.
|
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| IHC-P |
Use at an assay dependent concentration. PubMed: 22155235
|
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| WB |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
ICC
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
IHC-P
Use at an assay dependent concentration. PubMed: 22155235 |
|
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
翻訳後修飾
Polyubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex: polyubiquitination does not lead to degradation of DRD4 protein. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 25432 Rat
- SwissProt: P30729 Rat
- Unigene: 10159 Rat
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別名
- D(2C) dopamine receptor antibody
- D(4) dopamine receptor (D(2C) dopamine receptor). antibody
- D(4) dopamine receptor antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (4)
ab20424 は 4 報の論文で使用されています。
- Wysokinski A et al. Expression of Dopamine D1-4 and Serotonin 5-HT1A-3A Receptors in Blood Mononuclear Cells in Schizophrenia. Front Psychiatry 12:645081 (2021). PubMed: 33776821
- Bouvier ML et al. Sex-dependent alterations of dopamine receptor and glucose transporter density in rat hypothalamus under long-term clozapine and haloperidol medication. Brain Behav 10:e01694 (2020). PubMed: 32525610
- Wang Q et al. Cellular localization of dopamine receptors in the gastric mucosa of rats. Biochem Biophys Res Commun 417:197-203 (2012). IHC-P ; Rat . PubMed: 22155235
- Krishnan B et al. Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal. Eur J Neurosci 31:1027-42 (2010). PubMed: 20377617
