Anti-DRAM 抗体 [M3-P4B4] (ab64739)
Key features and details
- Mouse monoclonal [M3-P4B4] to DRAM
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-DRAM antibody [M3-P4B4]
DRAM 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [M3-P4B4] to DRAM -
由来種
Mouse -
アプリケーション
適用あり: WBmore details
適用なし: ICC/IF -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human DRAM aa 150-250.
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ポジティブ・コントロール
- This antibody gave a positive signal in HeLa whole cell lysate.
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特記事項
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 6.97% L-Arginine -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
M3-P4B4 -
ミエローマ
Ag 8563 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab64739の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
Use a concentration of 10 µg/ml. Predicted molecular weight: 26 kDa.
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特記事項 |
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WB
Use a concentration of 10 µg/ml. Predicted molecular weight: 26 kDa. |
ターゲット情報
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機能
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. -
配列類似性
Belongs to the DRAM/TMEM150 family. -
細胞内局在
Lysosome membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 55332 Human
- Omim: 610776 Human
- SwissProt: Q8N682 Human
- Unigene: 525634 Human
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別名
- Damage regulated autophagy modulator antibody
- Damage-regulated autophagy modulator 1 antibody
- Damage-regulated autophagy modulator antibody
see all
画像
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Anti-DRAM antibody [M3-P4B4] (ab64739) at 10 µg/ml + HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate (ab27252) at 20 µg
Secondary
Goat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Performed under reducing conditions.
Predicted band size: 26 kDa
Observed band size: 26 kDa
Exposure time: 20 minutes
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab64739 は 1 報の論文で使用されています。
- Zhang Y et al. FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells. Cells 11:N/A (2022). PubMed: 36552800