DL-AP5 sodium salt, NMDA glutamate site antagonist (ab120271)
Key features and details
- NMDA glutamate site antagonist. Water soluble form.
- CAS Number: 1303993-72-7
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
DL-AP5 sodium salt, NMDA glutamate site antagonist -
製品の詳細
NMDA glutamate site antagonist. Water soluble form. -
生理活性の詳細
Competitive NMDA receptor glutamate site antagonist. Water soluble form.
Also available in simple stock solutions (ab144498) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS 番号
1303993-72-7 -
構造式
製品の特性
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体系名
DL-2-Amino-5-phosphonopentanoic acid sodium salt -
分子量
219.11 -
分子式
C5H11NNaO5P -
PubChem 登録番号
52974251 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
O=P(O)(CCCC(N)C(=O)O)O[Na] -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (25)
ab120271 は 25 報の論文で使用されています。
- Bonnycastle K et al. Reversal of cell, circuit and seizure phenotypes in a mouse model of DNM1 epileptic encephalopathy. Nat Commun 14:5285 (2023). PubMed: 37648685
- Cheng J et al. Loss of O-GlcNAcylation on MeCP2 at Threonine 203 Leads to Neurodevelopmental Disorders. Neurosci Bull 38:113-134 (2022). PubMed: 34773221
- Bonnycastle K et al. FMRP Sustains Presynaptic Function via Control of Activity-Dependent Bulk Endocytosis. J Neurosci 42:1618-1628 (2022). PubMed: 34996816
- Mishra P & Narayanan R Conjunctive changes in multiple ion channels mediate activity-dependent intrinsic plasticity in hippocampal granule cells. iScience 25:103922 (2022). PubMed: 35252816
- Sanchez-Priego C et al. Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs. Cell Rep 39:110877 (2022). PubMed: 35649373