Anti-DFFB/CAD 抗体 (ab8406)
Key features and details
- Rabbit polyclonal to DFFB/CAD
- Suitable for: ICC/IF, WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-DFFB/CAD antibody
DFFB/CAD 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to DFFB/CAD -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IF, WBmore details -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide -
Concentration information loading... -
精製度
Affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab8406の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
Use a concentration of 5 µg/ml.
|
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| WB |
1/500 - 1/1000. Detects a band of approximately 39 kDa.
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| 特記事項 |
|---|
|
ICC/IF
Use a concentration of 5 µg/ml. |
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WB
1/500 - 1/1000. Detects a band of approximately 39 kDa. |
ターゲット情報
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機能
Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. -
配列類似性
Contains 1 CIDE-N domain. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 1677 Human
- Entrez Gene: 13368 Mouse
- Omim: 601883 Human
- SwissProt: O76075 Human
- SwissProt: O54788 Mouse
- Unigene: 133089 Human
- Unigene: 388918 Mouse
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別名
- CAD antibody
- Caspase activated deoxyribonuclease antibody
- Caspase activated DNase antibody
see all
画像
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Western blot - Anti-DFFB/CAD antibody (ab8406)All lanes : Anti-DFFB/CAD antibody (ab8406) at 1/500 dilution
Lane 1 : HeLa whole cell lysate
Lane 2 : K562 whole cell lysate
Lane 3 : Jurkat whole cell lysate
Lane 4 : Raji whole cell lysate -
Immunocytochemistry/ Immunofluorescence - Anti-DFFB/CAD antibody (ab8406)ab8406 at 20μg/ml staining DFFB/CAD in K562 cells by ICC/IF.
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Immunocytochemistry/ Immunofluorescence - Anti-DFFB/CAD antibody (ab8406)ab8406 at 5µg/ml staining DFFB/CAD in Jurkat cells by ICC/IF
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab8406 は 1 報の論文で使用されています。
- Yadav VK et al. Prostaglandin F2alpha-mediated activation of apoptotic signaling cascades in the corpus luteum during apoptosis: involvement of caspase-activated DNase. J Biol Chem 280:10357-67 (2005). PubMed: 15623530
