DFCA DA (5(6)-Carboxy-2',7'-dichlorofluorescein diacetate), Fluorogenic esterase substrate (ab145415)

製品の概要

  • 製品名
    DFCA DA (5(6)-Carboxy-2',7'-dichlorofluorescein diacetate), Fluorogenic esterase substrate
  • 製品の詳細
    Amine-reactive, fluorogenic, non-selective esterase substrate
  • 生理活性の詳細

    Amine-reactive, fluorogenic, non-selective esterase substrate. Hydrolyses to DFCA (ab145439) fluorophore intracellularly. Labels intact cells. 2,7-Dichlorofluorescein (ab146332) derivative and DCFDA N-succinimidyl ester (ab145286) precursor.

  • 精製度
    > 85%
  • CAS 番号
    127770-45-0
  • 構造式
    Chemical Structure

製品の特性

  • 励起波長
    495nm
  • 蛍光波長
    529nm
  • 体系名
    5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
  • 分子量
    529.28
  • 分子式
    C25H14Cl2O9
  • PubChem 登録番号
    16211578
  • 保存方法
    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性
    Soluble in DMSO
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記
    CC(=O)OC1=C(C=C2C(=C1)OC3=CC(=C(C=C3C24C5=C(C=C(C=C5)C(=O)O)C(=O)O4)Cl)OC(=O)C)Cl.CC(=O)OC1=C(C=C2C(=C1)OC3=CC(=C(C=C3C24C5=C(C=CC(=C5)C(=O)O)C(=O)O4)Cl)OC(=O)C)Cl
  • 由来

    Synthetic

  • 研究分野

参考文献

This product has been referenced in:
  • Janda E  et al. Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/Quinone Oxidoreductase 2: implications for neuroprotection. Autophagy :0 (2015). Read more (PubMed: 26046590) »
  • Guo C  et al. Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes. Toxicol Lett 224:93-100 (2014). Read more (PubMed: 24120425) »
  • Zamek-Gliszczynski MJ  et al. Pharmacokinetics of 5 (and 6)-carboxy-2',7'-dichlorofluorescein and its diacetate promoiety in the liver. J Pharmacol Exp Ther 304:801-9 (2003). Read more (PubMed: 12538836) »

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