Key features and details
- Potent and selective μ opioid receptor agonist
- CAS Number: 78123-71-4
- Purity: > 95%
- Soluble in water to 1 mg/ml
- Form / State: Solid
- Source: Synthetic
製品名DAMGO, mu opioid receptor agonist
製品の詳細Potent and selective μ opioid receptor agonist
Potent and selective μ opioid receptor agonist (Ki values are 2.0, >1000 and >1000 nM for opioid receptor subtypes μ, κ and δ, respectively). Partial central activity following systemic administration. Antinociceptive.
配列YAGFG (Modifications: C-terminal alcohol; Ala-2 = D-Ala; Phe-4 = N-Me)
保存方法Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
溶解性Soluble in water to 1 mg/ml
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120674 は 2 報の論文で使用されています。
- Bachmutsky I et al. Opioids depress breathing through two small brainstem sites. Elife 9:N/A (2020). PubMed: 32073401
- Bull FA et al. Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by ß-arrestin2 and c-Src. Sci Rep 7:9969 (2017). PubMed: 28855588