Anti-Cytomegalovirus IE1 and IE2 抗体 [CH160] - BSA and Azide free (ab53495)
Key features and details
- Mouse monoclonal [CH160] to Cytomegalovirus IE1 and IE2 - BSA and Azide free
- Suitable for: WB, ICC/IF
- Reacts with: Human cytomegalovirus
- Isotype: IgG1
製品の概要
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製品名
Anti-Cytomegalovirus IE1 and IE2 antibody [CH160] - BSA and Azide free -
製品の詳細
Mouse monoclonal [CH160] to Cytomegalovirus IE1 and IE2 - BSA and Azide free -
由来種
Mouse -
特異性
ab53495 reacts with cytomegalovirus IE1 and IE2. -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Human cytomegalovirus -
免疫原
Tissue, cells or virus corresponding to Cytomegalovirus IE1 and IE2. HCMV AD169 IC Extract.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: PBS -
キャリア・フリー
はい -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
CH160 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53495の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 10 µg/ml.
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ICC/IF |
Use a concentration of 10 µg/ml.
|
特記事項 |
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WB
Use a concentration of 10 µg/ml. |
ICC/IF
Use a concentration of 10 µg/ml. |
ターゲット情報
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関連性
The IE1/2 transcriptional control region of human cytomegalovirus drives the expression of the HCMV major immediate-early genes (UL123-122), which encode proteins necessary for initiation of the virus replicative cycle. Nucleotide sequence polymorphism in this region of the viral genome could account for variations in the replication of human cytomegalovirus strains. -
参照データベース
- Entrez Gene: 1487821 Human cytomegalovirus
- Entrez Gene: 1487822 Human cytomegalovirus
- SwissProt: P13202 Human cytomegalovirus
- SwissProt: P19893 Human cytomegalovirus
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別名
- 45 kDa immediate-early protein 2 antibody
- 55 kDa immediate-early protein 2 antibody
- HCMV antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (17)
ab53495 は 17 報の論文で使用されています。
- Zhang X et al. Human Cytomegalovirus-IE2 Affects Embryonic Liver Development and Survival in Transgenic Mouse. Cell Mol Gastroenterol Hepatol 14:494-511 (2022). PubMed: 35569816
- Bergamelli M et al. Human Cytomegalovirus Modifies Placental Small Extracellular Vesicle Composition to Enhance Infection of Fetal Neural Cells In Vitro. Viruses 14:N/A (2022). PubMed: 36146834
- Wang H et al. Cytomegalovirus-specific neutralizing antibodies effectively prevent uncontrolled infection after allogeneic hematopoietic stem cell transplantation. iScience 25:105065 (2022). PubMed: 36147955
- Vezzani G et al. The Human Cytomegalovirus UL116 Glycoprotein Is a Chaperone to Control gH-Based Complexes Levels on Virions. Front Microbiol 12:630121 (2021). PubMed: 33889136
- Branch KM et al. Productive Infection of Human Breast Cancer Cell Lines with Human Cytomegalovirus (HCMV). Pathogens 10:N/A (2021). PubMed: 34070980