Anti-CXXC5 抗体 (ab106533)
Key features and details
- Rabbit polyclonal to CXXC5
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CXXC5 antibody
CXXC5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CXXC5 -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IF, IHC-P, WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide, 15 aa from near the amino terminus of human CXXC5 (NP_057547).
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ポジティブ・コントロール
- Human brain tissue lysate.
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特記事項
Predicted to not cross-react with other CXXC protein family members.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
一次抗体 備考
Predicted to not cross-react with other CXXC protein family members. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106533の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
Use a concentration of 20 µg/ml.
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IHC-P |
Use a concentration of 2.5 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 33 kDa. Isoform 2 predicted molecular weight 24 kDa
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特記事項 |
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ICC/IF
Use a concentration of 20 µg/ml. |
IHC-P
Use a concentration of 2.5 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 33 kDa. Isoform 2 predicted molecular weight 24 kDa |
ターゲット情報
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機能
May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. -
配列類似性
Contains 1 CXXC-type zinc finger. -
細胞内局在
Nucleus. Cytoplasm. Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 51523 Human
- Omim: 612752 Human
- SwissProt: Q7LFL8 Human
- Unigene: 189119 Human
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製品の状態
There are 2 isoforms produced by alternative splicing. -
別名
- CF5 antibody
- CXXC finger 5 protein antibody
- CXXC finger protein 5 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab106533 は 2 報の論文で使用されています。
- Yasar P et al. Estradiol-Estrogen Receptor a Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway. Sci Rep 6:37808 (2016). WB ; Human . PubMed: 27886276
- Kim HY et al. CXXC5 is a transcriptional activator of Flk-1 and mediates bone morphogenic protein-induced endothelial cell differentiation and vessel formation. FASEB J 28:615-26 (2014). WB ; Mouse . PubMed: 24136587