Anti-CTGF 抗体 (ab6992)
Key features and details
- Rabbit polyclonal to CTGF
- Suitable for: IHC-P, ICC/IF, IHC-FoFr, WB, IHC-Fr, IP
- Reacts with: Mouse, Rat, Sheep, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Anti-CTGF antibody
CTGF 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CTGF -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, ICC/IF, IHC-FoFr, WB, IHC-Fr, IPmore details -
種交差性
交差種: Mouse, Rat, Sheep, Human
交差が予測される動物種: Cow -
免疫原
-
ポジティブ・コントロール
- human hippocampal protein extracts (see Ueberham et al paper).
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab6992の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P | (10) |
Use at an assay dependent concentration.
|
ICC/IF | (4) |
Use at an assay dependent concentration.
|
IHC-FoFr | (1) |
Use at an assay dependent concentration.
|
WB | (10) |
Use at an assay dependent concentration. Predicted molecular weight: 38 kDa.
Block membrane in 4% BSA in Tris-buffered saline containing 0.05% Tween 20 (TBST). See Fu M et al. |
IHC-Fr | (2) |
Use at an assay dependent concentration.
See Ueberham et al. |
IP |
Use at an assay dependent concentration. PubMed: 16100286
|
特記事項 |
---|
IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
IHC-FoFr
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 38 kDa. Block membrane in 4% BSA in Tris-buffered saline containing 0.05% Tween 20 (TBST). See Fu M et al. |
IHC-Fr
Use at an assay dependent concentration. See Ueberham et al. |
IP
Use at an assay dependent concentration. PubMed: 16100286 |
ターゲット情報
-
機能
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. -
組織特異性
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. -
配列類似性
Belongs to the CCN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 TSP type-1 domain.
Contains 1 VWFC domain. -
細胞内局在
Secreted > extracellular space > extracellular matrix. Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 281103 Cow
- Entrez Gene: 1490 Human
- Entrez Gene: 14219 Mouse
- Entrez Gene: 64032 Rat
- Omim: 121009 Human
- SwissProt: O18739 Cow
- SwissProt: P29279 Human
- SwissProt: P29268 Mouse
see all -
別名
- CCN 2 antibody
- CCN family member 2 antibody
- CCN2 antibody
see all
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (262)
ab6992 は 262 報の論文で使用されています。
- Zhang Y et al. miR-212 promotes renal interstitial fibrosis by inhibiting hypoxia-inducible factor 1-a inhibitor. Mol Med Rep 23:N/A (2021). PubMed: 33495813
- Lyu L et al. Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress. J Cell Mol Med 25:3136-3148 (2021). PubMed: 33560596
- Zhu F et al. Tubular Numb promotes renal interstitial fibrosis via modulating HIF-1a protein stability. Biochim Biophys Acta Mol Basis Dis 1867:166081 (2021). PubMed: 33486098
- Tokuda K et al. Development of a novel knee contracture mouse model by immobilization using external fixation. Connect Tissue Res N/A:1-14 (2021). PubMed: 33602048
- Liu Y et al. Inhibiting miR-1 attenuates pulmonary arterial hypertension in rats. Mol Med Rep 23:N/A (2021). PubMed: 33604679