Anti-Creatine Kinase MB 抗体 [CK1] (ab404)
Key features and details
- Mouse monoclonal [CK1] to Creatine Kinase MB
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Creatine Kinase MB antibody [CK1]
Creatine Kinase MB 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [CK1] to Creatine Kinase MB -
由来種
Mouse -
特異性
CK1 recognises human creatine kinase MB isoenzyme. Its affinity for the creatine kinase BB isoenzyme is greater than its affinity for creatine kinase MB isoenzyme. hCK-MB - 100% hCK-BB - 182% hCK-MM - 7.3% Affinity constant: 2x109 l/mol human CK-MB. -
種交差性
交差種: Human -
免疫原
Full length native protein (purified) (Human).
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特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 6.00
Preservative: 0.095% Sodium azide
Constituents: 0.335% PBS, 1.0878% Sodium citrate, 0.9% Sodium chloride -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
CK1 -
ミエローマ
unknown -
アイソタイプ
IgG1 -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
ターゲット情報
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関連性
Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa. -
細胞内局在
Cytoplasmic and Mitochondrial -
参照データベース
- Entrez Gene: 1152 Human
- Entrez Gene: 1158 Human
- Omim: 123310 Human
- SwissProt: P06732 Human
- SwissProt: P12277 Human
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別名
- B-CK antibody
- brain creatine kinase antibody
- CKBB antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (2)
ab404 は 2 報の論文で使用されています。
- Garay F et al. Surface plasmon resonance aided electrochemical immunosensor for CK-MB determination in undiluted serum samples. Anal Bioanal Chem 397:1873-81 (2010). PubMed: 20449577
- Crawford RM et al. Creatine kinase is physically associated with the cardiac ATP-sensitive K+ channel in vivo. FASEB J 16:102-4 (2002). PubMed: 11729098