Anti-COX2 / Cyclooxygenase 2 抗体 [5E10/D10] (ab701)
Key features and details
- Mouse monoclonal [5E10/D10] to COX2 / Cyclooxygenase 2
- Suitable for: WB
- Reacts with: Sheep
- Isotype: IgG1
製品の概要
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製品名
Anti-COX2 / Cyclooxygenase 2 antibody [5E10/D10]
COX2 / Cyclooxygenase 2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [5E10/D10] to COX2 / Cyclooxygenase 2 -
由来種
Mouse -
特異性
COX-2. No cross-reactivity with Cox-1. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Sheep -
免疫原
Full length native protein (purified) corresponding to Human COX2/ Cyclooxygenase 2. COX-2 purified from HL-60 cells
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特記事項
Please note that we have received a report from a customer working with this antibody that they obtain two stong bands in WB (one between 40 - 50kDa and other other between 62 - 83kDa). A single band at around 72kDa is expected.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide
FCS free -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
モノクローナル -
クローン名
5E10/D10 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab701の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 0.5 - 1 µg/ml.
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特記事項 |
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WB
Use a concentration of 0.5 - 1 µg/ml. |
ターゲット情報
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機能
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. -
パスウェイ
Lipid metabolism; prostaglandin biosynthesis. -
配列類似性
Belongs to the prostaglandin G/H synthase family.
Contains 1 EGF-like domain. -
翻訳後修飾
S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561. -
細胞内局在
Microsome membrane. Endoplasmic reticulum membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 443460 Sheep
- SwissProt: P79208 Sheep
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別名
- COX 2 antibody
- COX-2 antibody
- COX2 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (0)
ab701 は論文での使用が確認できていません。