Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4615] to Cortisol Binding Globulin - BSA and Azide free
- Suitable for: WB
- Reacts with: Human
製品名Anti-Cortisol Binding Globulin antibody [EPR4615] - BSA and Azide free
Cortisol Binding Globulin 一次抗体 製品一覧
製品の詳細Rabbit monoclonal [EPR4615] to Cortisol Binding Globulin - BSA and Azide free
アプリケーション適用あり: WBmore details
適用なし: ICC,IHC-P or IP
Synthetic peptide within Human Cortisol Binding Globulin aa 100-200. The exact sequence is proprietary.
ab247930 is the carrier-free version of ab110648 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.
Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Ab247930 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.
Maxpar® is a trademark of Fluidigm Canada Inc.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Concentration information loading...
Our Abpromise guarantee covers the use of ab247930 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent concentration. Detects a band of approximately 60 kDa (predicted molecular weight: 45 kDa).|
機能Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
組織特異性Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.
関連疾患Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency) [MIM:611489]. CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue.
配列類似性Belongs to the serpin family.
翻訳後修飾N-glycosylated; binds 5 oligosaccharide chains.
Glycosylation in position Asn-260 is needed for steroid binding.
- Information by UniProt
- CBG antibody
- CBG_HUMAN antibody
- corticosteroid binding globulin antibody
All lanes : Anti-Cortisol Binding Globulin antibody [EPR4615] (ab110648) at 1/1000 dilution
Lane 1 : Human fetal artery lysate
Lane 2 : Human plasma lysate
Lane 3 : Human placenta lysate
Lysates/proteins at 10 µg per lane.
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 45 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted?
This data was developed using ab110648, the same antibody clone in a different buffer formulation.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.