Anti-Cortisol Binding Globulin 抗体 [EPR4615] (ab110648)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4615] to Cortisol Binding Globulin
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
-
製品名
Anti-Cortisol Binding Globulin antibody [EPR4615]
Cortisol Binding Globulin 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR4615] to Cortisol Binding Globulin -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: ICC/IF,IHC-P or IP -
種交差性
交差種: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
ポジティブ・コントロール
- Human fetal artery, plasma and placenta lysates
-
特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR4615 -
アイソタイプ
IgG -
研究分野
関連製品
-
Alternative Versions
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab110648の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 45 kDa).
|
特記事項 |
---|
WB
1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 45 kDa). |
ターゲット情報
-
機能
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. -
組織特異性
Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. -
関連疾患
Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency) [MIM:611489]. CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. -
配列類似性
Belongs to the serpin family. -
翻訳後修飾
N-glycosylated; binds 5 oligosaccharide chains.
Glycosylation in position Asn-260 is needed for steroid binding. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 866 Human
- Omim: 122500 Human
- SwissProt: P08185 Human
- Unigene: 532635 Human
-
別名
- CBG antibody
- CBG_HUMAN antibody
- corticosteroid binding globulin antibody
see all
画像
-
All lanes : Anti-Cortisol Binding Globulin antibody [EPR4615] (ab110648) at 1/1000 dilution
Lane 1 : Human fetal artery lysate
Lane 2 : Human plasma lysate
Lane 3 : Human placenta lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 45 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted?
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab110648 は 1 報の論文で使用されています。
- Wang C et al. Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure. PeerJ 9:e11009 (2021). PubMed: 33763303