Anti-Conjugated Noradrenaline 抗体 (ab6454)
Key features and details
- Rabbit polyclonal to Conjugated Noradrenaline
- Suitable for: ELISA, IHC-Fr
- Reacts with: Species independent
- Isotype: IgG
製品の概要
-
製品名
Anti-Conjugated Noradrenaline antibody -
製品の詳細
Rabbit polyclonal to Conjugated Noradrenaline -
由来種
Rabbit -
特異性
Using catecholamine-Glutaraldehyde-BSA conjugates, antibody specificity was performed with an ELISA test by competition experiments, as follows: (a) unconjugated or conjugated catecholamine concentration at half displacement (b) Non-reduced conjugateCompound Cross-reactivity ratio (a) Noradrenaline 1 Octopamine 1/31 Dopamine 1/70 Adrenaline 1/177 Noradrenaline (b) 1/316 L-DOPA, Tyramine, unconjugated Noradrenaline 1/>5000 -
アプリケーション
適用あり: ELISA, IHC-Frmore details -
種交差性
交差種: Species independent -
免疫原
Synthetic noradrenaline conjugated to protein carriers (PC).
-
特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading... -
精製度
Ammonium Sulphate Precipitation -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab6454 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA | ||
| IHC-Fr |
ELISA: assay dependent.
Not tested in other applications.
Optimal dilutions / concentrations should be determined by the end user.
ターゲット情報
-
関連性
Noradrenaline (NA) is a catecholamine neurotransmitter at postganglionic sympathetic fibres, produced following a series of steps from the essential amino acid phenylalanine. Terminal postganglionic sympathetic fibres have varicosities (where NA is synthesised and stored) which form synapses with the effector organ. The adrenal medulla is a major source of catecholamines (such as NA and adrenaline), however, most of the NA produced in the adrenal medulla is converted into adrenaline. NA is key in the fight-or-flight response and also directly increases heart rate, energy release from fat, and muscle readiness.
データシートおよび資料
参考文献 (2)
ab6454 は 2 報の論文で使用されています。
- Aschrafi A et al. Angiotensin II mediates the axonal trafficking of tyrosine hydroxylase and dopamine ß-hydroxylase mRNAs and enhances norepinephrine synthesis in primary sympathetic neurons. J Neurochem 150:666-677 (2019). PubMed: 31306490
- Arima Y et al. Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit. Elife 6:N/A (2017). PubMed: 28809157
