Anti-CNBP 抗体 (ab272676)
Key features and details
- Rabbit polyclonal to CNBP
- Suitable for: ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-CNBP antibody
CNBP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CNBP -
由来種
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species ICC/IF HumanWB Human
-
免疫原
Recombinant fragment corresponding to Human CNBP aa 1-100.
Database link: P62633 -
ポジティブ･コントロール
- WB: RT4, U-251 MG cells, Human liver and tonsil. IF: SH-SY5Y cells.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272676 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| アプリケーション | Species |
|---|---|
| ICC/IF |
Human
|
| WB |
Human
|
| All applications |
Mouse
Rat
Orangutan
|
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
|
|
| WB |
Use a concentration of 0.04 - 0.4 µg/ml.
|
| 特記事項 |
|---|
|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
|
WB
Use a concentration of 0.04 - 0.4 µg/ml. |
ターゲット情報
-
機能
Single stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression. -
組織特異性
Present in all tissues examined. -
関連疾患
Defects in CNBP are the cause of dystrophia myotonica type 2 (DM2) [MIM:602668]; also known as proximal myotonic myopathy (PROMM). A multisystem disease characterized by the association of proximal muscle weakness with myotonia, cardiac manifestations and cataract. Additional features can include hyperhidrosis, testicular atrophy, insulin resistance and diabetes and central nervous system anomalies in rare cases. Note=The causative mutation is a CCTG expansion (mean approximately 5000 repeats) located in intron 1 of the CNBP gene. -
配列類似性
Contains 7 CCHC-type zinc fingers. -
細胞内局在
Cytoplasm. Endoplasmic reticulum. - Information by UniProt
-
参照データベース
- Entrez Gene: 7555 Human
- Entrez Gene: 12785 Mouse
- Entrez Gene: 64530 Rat
- Omim: 116955 Human
- SwissProt: P62633 Human
- SwissProt: P53996 Mouse
- SwissProt: P62634 Rat
- Unigene: 518249 Human
see all -
別名
- CCHC type zinc finger nucleic acid binding protein antibody
- Cellular nucleic acid binding protein antibody
- Cellular nucleic acid-binding protein antibody
see all
画像
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Western blot - Anti-CNBP antibody (ab272676)All lanes : Anti-CNBP antibody (ab272676) at 0.4 µg/ml
Lane 1 : RT4 cells (Human urinary bladder cancer cell line)
Lane 2 : U-251 MG cells (Human brain glioma cell line)
Lane 3 : Human plasma
Lane 4 : Human liver tissue
Lane 5 : Human tonsil tissue -
Immunocytochemistry/ Immunofluorescence - Anti-CNBP antibody (ab272676)PFA fixed, Triton X-100 permeablized SH-SY5Y cells (human neuroblastoma cell line from bone marrow) labeling CNBP (green) using ab272676 at 2 ug/ml in ICC/IF analysis.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab272676 は論文での使用が確認できていません。
