Anti-BOTOX 抗体 (ab20641)
Key features and details
- Rabbit polyclonal to BOTOX
- Suitable for: ELISA, WB
- Reacts with: Species independent
- Isotype: IgG
製品の概要
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製品名
Anti-BOTOX antibody
BOTOX 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to BOTOX -
由来種
Rabbit -
特異性
Clostridium botulinum Type A Neurotoxin. -
アプリケーション
適用あり: ELISA, WBmore details -
種交差性
交差種: Species independent -
免疫原
Full length protein corresponding to BOTOX.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Constituents: 2.68% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab20641の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
1/10000.
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WB | (1) |
Use at an assay dependent dilution. Predicted molecular weight: 149 kDa.
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特記事項 |
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ELISA
1/10000. |
WB
Use at an assay dependent dilution. Predicted molecular weight: 149 kDa. |
ターゲット情報
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関連性
Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25. -
別名
- Atx antibody
- BotA antibody
- BOTOX antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab20641 は 5 報の論文で使用されています。
- Bagramyan K et al. Substrates and controls for the quantitative detection of active botulinum neurotoxin in protease-containing samples. Anal Chem 85:5569-76 (2013). PubMed: 23656526
- Bagramyan K & Kalkum M Ultrasensitive detection of botulinum neurotoxins and anthrax lethal factor in biological samples by ALISSA. Methods Mol Biol 739:23-36 (2011). PubMed: 21567315
- Scotcher MC et al. Epitope characterization and variable region sequence of f1-40, a high-affinity monoclonal antibody to botulinum neurotoxin type a (Hall strain). PLoS ONE 4:e4924 (2009). WB . PubMed: 19290051
- Scotcher MC et al. Characterization of the epitope region of F1-2 and F1-5, two monoclonal antibodies to Botulinum neurotoxin type A. Hybridoma (Larchmt) 28:315-25 (2009). WB . PubMed: 19857112
- Bagramyan K et al. Attomolar detection of botulinum toxin type A in complex biological matrices. PLoS ONE 3:e2041 (2008). PubMed: 18446228