製品の概要

  • 製品名

    Clioquinol, Metal chelator and ionophore
  • 製品の詳細

    Metal chelator and ionophore
  • 生理活性の詳細

    Metal chelator and ionophore with beneficial effects in animal models of neurodegenerative diseases (Alzheimer's, Parkinson's and Huntington's disease). Effects on Alzheimer's disease attributed to copper and zinc chelation or increased level of a metalloprotease. Other actions reported including iron chelation, inhibition of Huntington expression from its mRNA, proteasome inhibition when complexed with copper, and stimulation of tumor necrosis factor-α secretion. Also inhibitor of CLK-1/MCLK1 (an aging-associated protein).
  • 精製度

    > 97%
  • CAS 番号

    130-26-7
  • 構造式

    Chemical Structure

製品の特性

参考文献

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