Anti-CLEC2D 抗体 [EPR6584(2)] (ab151738)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6584(2)] to CLEC2D
- Suitable for: Flow Cyt (Intra), WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-CLEC2D antibody [EPR6584(2)]
CLEC2D 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR6584(2)] to CLEC2D -
由来種
Rabbit -
アプリケーション
適用あり: Flow Cyt (Intra), WBmore details
適用なし: ICC/IF,IHC-P or IP -
種交差性
交差種: Human
非交差種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- Human lymph node, Saos2, and U-87 MG lysates; Saos2 cells.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20ºC. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPR6584(2) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab151738の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt (Intra) |
1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
|
WB |
1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
|
特記事項 |
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Flow Cyt (Intra)
1/10 - 1/100. ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
WB
1/1000 - 1/10000. Predicted molecular weight: 22 kDa. |
ターゲット情報
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機能
Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. -
組織特異性
Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T and B lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells. -
配列類似性
Contains 1 C-type lectin domain. -
細胞内局在
Endoplasmic reticulum and Cell membrane. Cell surface. - Information by UniProt
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参照データベース
- Entrez Gene: 29121 Human
- Omim: 605659 Human
- SwissProt: Q9UHP7 Human
- Unigene: 268326 Human
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別名
- C type lectin related f antibody
- C type lectin superfamily 2, member D antibody
- C-type lectin domain family 2 member D antibody
see all
画像
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Intracellular flow cytometric analysis of permeabilized Saos2 cells labeling CLEC2D with ab151738 at 1/10 dilution (red), compared to a nonspecific control antibody (green).
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All lanes : Anti-CLEC2D antibody [EPR6584(2)] (ab151738) at 1/1000 dilution
Lane 1 : Human lymph node lysate
Lane 2 : Saos2 cell lysate
Lane 3 : U-87 MG cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 22 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab151738 は 2 報の論文で使用されています。
- Li J et al. IFN-γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection. Clin Transl Immunology 10:e1353 (2021). PubMed: 34754450
- Raikwar N et al. Renal denervation and CD161a immune ablation prevent cholinergic hypertension and renal sodium retention. Am J Physiol Heart Circ Physiol 317:H517-H530 (2019). PubMed: 31172810