Anti-CIAPIN1 抗体 (ab154904)
Key features and details
- Rabbit polyclonal to CIAPIN1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-CIAPIN1 antibody
CIAPIN1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CIAPIN1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Recombinant fragment, corresponding to a region within amino acids 1-312 of Human CIAPIN1 (Uniprot ID: Q6FI81).
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ポジティブ・コントロール
- Jurkat, Raji, K562, THP1, HL60, NCI-H929, NIH 3T3, JC and BCL1 whole cell lysates; Human SkHep1 xenograft tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab154904の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 34 kDa.
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IHC-P |
1/100 - 1/1000.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 34 kDa. |
IHC-P
1/100 - 1/1000. |
ターゲット情報
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機能
May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells. -
組織特異性
Ubiquitously expressed. Highly expressed in heart, liver and pancreas. -
配列類似性
Belongs to the anamorsin family. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 57019 Human
- Entrez Gene: 109006 Mouse
- Omim: 608943 Human
- SwissProt: Q6FI81 Human
- SwissProt: Q8WTY4 Mouse
- Unigene: 4900 Human
- Unigene: 27582 Mouse
- Unigene: 472546 Mouse
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別名
- 2810413N20Rik antibody
- Anamorsin antibody
- CIAPIN 1 antibody
see all
画像
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All lanes : Anti-CIAPIN1 antibody (ab154904) at 1/1000 dilution
Lane 1 : Jurkat whole cell lysate
Lane 2 : Raji whole cell lysate
Lane 3 : K562 whole cell lysate
Lane 4 : THP1 whole cell lysate
Lane 5 : HL60 whole cell lysate
Lane 6 : NCI-H929 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 34 kDa
10% SDS PAGE -
All lanes : Anti-CIAPIN1 antibody (ab154904) at 1/3000 dilution
Lane 1 : NIH 3T3 whole cell lysate
Lane 2 : JC whole cell lysate
Lane 3 : BCL1 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 34 kDa
10% SDS PAGE -
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human SkHep1 xenograft tissue labeling CIAPIN1 with ab154904 at 1/500 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab154904 は 4 報の論文で使用されています。
- Zheng J et al. MiRNA-195-5p Functions as a Tumor Suppressor and a Predictive of Poor Prognosis in Non-small Cell Lung Cancer by Directly Targeting CIAPIN1. Pathol Oncol Res N/A:N/A (2019). PubMed: 30637589
- Chen X et al. Andrographolide Suppresses MV4-11 Cell Proliferation through the Inhibition of FLT3 Signaling, Fatty Acid Synthesis and Cellular Iron Uptake. Molecules 22:N/A (2017). PubMed: 28858244
- Wang JH et al. Upregulation of microRNA-143 reverses drug resistance in human breast cancer cells via inhibition of cytokine-induced apoptosis inhibitor 1. Oncol Lett 13:4695-4700 (2017). WB . PubMed: 28588724
- Wang X et al. Cytokine-induced apoptosis inhibitor 1 inhibits the growth and proliferation of multiple myeloma. Mol Med Rep 12:2056-62 (2015). PubMed: 25901506