製品の概要

  • 製品名
    Anti-Chromogranin A antibody [LK2H10 + PHE5]
    Chromogranin A 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [LK2H10 + PHE5] to Chromogranin A
  • 由来種
    Mouse
  • アプリケーション
    適用あり: ICC/IF, IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Rat, Human, Monkey
  • 免疫原

    Human pheochromocytoma

  • エピトープ
    Although the epitopes for these two clones are not precisely mapped, experimental data suggest that they are different.
  • ポジティブ・コントロール
    • Pancreas, adrenal gland, bowel and thyroid
  • 特記事項

    Please note that this antibody is an oligoclonal antibody. It is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies have not only the specificity and batch-to-batch consistency of a monoclonal antibody, but also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen. 

     

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab715 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration.
IHC-P 1/50 - 1/100.
IHC-Fr Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • 配列類似性
    Belongs to the chromogranin/secretogranin protein family.
  • 翻訳後修飾
    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • 細胞内局在
    Secreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt
  • 参照データベース
  • 製品の状態
    According to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
  • 別名
    • beta Granin antibody
    • betagranin (N-terminal fragment of chromogranin A) antibody
    • catestatin antibody
    • CgA antibody
    • CHG A antibody
    • Chga antibody
    • chromofungin antibody
    • Chromogranin A antibody
    • Chromogranin A parathyroid secretory protein 1 antibody
    • Chromogranin A precursor antibody
    • ChromograninA antibody
    • CMGA_HUMAN antibody
    • ER-37 antibody
    • Pancreastatin antibody
    • Parastatin antibody
    • Parathyroid secretory protein 1 antibody
    • Pituitary secretory protein I antibody
    • Secretory protein I antibody
    • SP I antibody
    • SP-I antibody
    • SP1 antibody
    • SPI antibody
    • vasostatin 2 antibody
    • Vasostatin antibody
    • Vasostatin I antibody
    • Vasostatin II antibody
    • vasostatin-2 antibody
    see all

画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of neuroendocrine tumor tissue labeling Chromogranin A with ab715.

  • Immunocytochemistry/ Immunofluorescence analysis of human prostate cells labeling Chromogranin A with ab715 at 1/200 dilution (green). Cells were fixed with 4% paraformaldehyde and permeabilized with 0.8% Triton X-100. A donkey anti-mouse (Alexa Fluor® 647) was used as the secondary antibody at 1/400 dilution.

    See Abreview

参考文献

This product has been referenced in:
  • Burke AP  et al. Carcinoids of the jejunum and ileum: an immunohistochemical and clinicopathologic study of 167 cases. Cancer 79:1086-93 (1997). Read more (PubMed: 9070484) »
  • Angelsen A  et al. Neuroendocrine differentiation in carcinomas of the prostate: do neuroendocrine serum markers reflect immunohistochemical findings? Prostate 30:1-6 (1997). Read more (PubMed: 9018329) »
See all 8 Publications for this product

レビューと Q&A

1-2 of 2 Q&A

Question
Answer

Thank you for your enquiry and patience. I have confirmed with the laboratory that the ab715 antibody's concentration is 200ug/ml and the purification is by protein G chromatography. I hope this information will be useful to you. If you require any further information, please do not hesitate to contact me.

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Answer

Thank you for your enquiry. Unfortunately, we do not have more information about this antibody. We will update the on-line datasheet of this product as soon as we get more data. We apologize for any inconvenience caused. If you have any questions in the meantime, please do let us know.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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