Anti-Chromogranin A 抗体 (ab15160)
Key features and details
- Rabbit polyclonal to Chromogranin A
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Chromogranin A antibody
Chromogranin A 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Chromogranin A -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Monkey
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免疫原
Recombinant fragment within Human Chromogranin A aa 250 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P10645 -
特記事項
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab15160の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (3) |
1/100.
|
| 特記事項 |
|---|
|
WB
1/100. |
ターゲット情報
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機能
Pancreastatin strongly inhibits glucose induced insulin release from the pancreas. -
配列類似性
Belongs to the chromogranin/secretogranin protein family. -
翻訳後修飾
Sulfated on tyrosine residues and/or contains sulfated glycans.
O-glycosylated with core 1 or possibly core 8 glycans. -
細胞内局在
Secreted. Neuroendocrine and endocrine secretory granules. - Information by UniProt
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参照データベース
- Entrez Gene: 1113 Human
- Entrez Gene: 12652 Mouse
- Omim: 118910 Human
- SwissProt: P10645 Human
- SwissProt: P26339 Mouse
- Unigene: 150793 Human
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製品の状態
According to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa. -
別名
- beta Granin antibody
- betagranin (N-terminal fragment of chromogranin A) antibody
- catestatin antibody
see all
画像
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Western blot - Anti-Chromogranin A antibody (ab15160)Chromogranin A is easily fragmented and both bands observed in the Western Blot above are believed to correspond to Chromogranin A.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (181)
ab15160 は 181 報の論文で使用されています。
- Yagishita Y et al. Constitutive Activation of Nrf2 in Mice Expands Enterogenesis in Small Intestine Through Negative Regulation of Math1. Cell Mol Gastroenterol Hepatol 11:503-524 (2021). PubMed: 32896624
- Chen Q et al. Paneth cell-derived growth factors support tumorigenesis in the small intestine. Life Sci Alliance 4:N/A (2021). PubMed: 33372038
- Jones BC et al. Paediatric gastric organoids as a tool for disease modelling and clinical translation. Pediatr Surg Int 37:317-324 (2021). PubMed: 33495862
- Quintero M et al. Cdk5rap3 is essential for intestinal Paneth cell development and maintenance. Cell Death Dis 12:131 (2021). PubMed: 33504792
- Yamazaki D et al. Role of adenomatous polyposis coli in proliferation and differentiation of colon epithelial cells in organoid culture. Sci Rep 11:3980 (2021). PubMed: 33597597