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ab15160 は 96 報の論文で使用されています。

  • Wartenberg H  et al. The Origin of a New Progenitor Stem Cell Group in Human Development. Adv Anat Embryol Cell Biol 230:1-70 (2019). PubMed: 30543033
  • Guo H  et al. ONECUT2 is a driver of neuroendocrine prostate cancer. Nat Commun 10:278 (2019). PubMed: 30655535
  • Clark DPQ  et al. Inflammation in Traumatic Brain Injury: Roles for Toxic A1 Astrocytes and Microglial-Astrocytic Crosstalk. Neurochem Res N/A:N/A (2019). PubMed: 30661228
  • Cai Y  et al. Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation. Cell Discov 5:7 (2019). PubMed: 30701081
  • Larraufie P  et al. Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery. Cell Rep 26:1399-1408.e6 (2019). PubMed: 30726726
  • Konno T  et al. Role of lysophosphatidic acid in proliferation and differentiation of intestinal epithelial cells. PLoS One 14:e0215255 (2019). PubMed: 31017922
  • Zha JM  et al. Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5+ Stem Cells via Inhibition of Wnt and Notch Signaling. Cell Mol Gastroenterol Hepatol 7:255-274 (2019). PubMed: 30686779
  • Antas P  et al. SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating ß-Catenin Nuclear Localization. Cell Rep 26:2266-2273.e4 (2019). PubMed: 30811977
  • Liu R  et al. Lgr5+ intestinal stem cell sorting and organoid culture. Animal Model Exp Med 2:132-135 (2019). PubMed: 31392307
  • Wilke G  et al. A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability. Cell Host Microbe 26:123-134.e8 (2019). PubMed: 31231046
  • Jijon HB  et al. Intestinal epithelial cell-specific RARa depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system. Mucosal Immunol 11:703-715 (2018). PubMed: 29139475
  • Sznurkowska MK  et al. Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development. Dev Cell 46:360-375.e5 (2018). PubMed: 30057275
  • Byrnes LE  et al. Lineage dynamics of murine pancreatic development at single-cell resolution. Nat Commun 9:3922 (2018). PubMed: 30254276
  • Tomic G  et al. Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration. Cell Stem Cell 23:436-443.e7 (2018). PubMed: 30100168
  • Shaib AH  et al. Paralogs of the Calcium-Dependent Activator Protein for Secretion Differentially Regulate Synaptic Transmission and Peptide Secretion in Sensory Neurons. Front Cell Neurosci 12:304 (2018). PubMed: 30254567
  • Owen RP  et al. Single cell RNA-seq reveals profound transcriptional similarity between Barrett's oesophagus and oesophageal submucosal glands. Nat Commun 9:4261 (2018). PubMed: 30323168
  • Martinez-Valbuena I  et al. Interaction of amyloidogenic proteins in pancreatic ß cells from subjects with synucleinopathies. Acta Neuropathol N/A:N/A (2018). IHC-P ; Human . PubMed: 29536165
  • Norum JH  et al. The tankyrase inhibitor G007-LK inhibits small intestine LGR5+stem cell proliferation without altering tissue morphology. Biol Res 51:3 (2018). IHC-P ; Mouse . PubMed: 29316982
  • Chua CW  et al. Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation. Elife 7:N/A (2018). PubMed: 29334357
  • Eguchi T  et al. Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment. PLoS One 13:e0191109 (2018). PubMed: 29415026
  • Guarize J  et al. MicroRNA expression profile in primary lung cancer cells lines obtained by endobronchial ultrasound transbronchial needle aspiration. J Thorac Dis 10:408-415 (2018). PubMed: 29600073
  • Lyons J  et al. The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile. PLoS Biol 16:e2002417 (2018). PubMed: 29596476
  • Herring CA  et al. Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut. Cell Syst 6:37-51.e9 (2018). PubMed: 29153838
  • Smith NR  et al. Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations. Cell Mol Gastroenterol Hepatol 6:79-96 (2018). PubMed: 29928673
  • Thomsen SK  et al. Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic ß-cells. Nat Genet 50:1122-1131 (2018). PubMed: 30054598
  • Curtin C  et al. A physiologically relevant 3D collagen-based scaffold-neuroblastoma cell system exhibits chemosensitivity similar to orthotopic xenograft models. Acta Biomater 70:84-97 (2018). WB . PubMed: 29447961
  • Zhang L  et al. Establishing estrogen-responsive mouse mammary organoids from single Lgr5+ cells. Cell Signal 29:41-51 (2017). PubMed: 27511963
  • Wieck MM  et al. Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche. Cell Mol Gastroenterol Hepatol 3:367-388.e1 (2017). PubMed: 28462379
  • Liu M  et al. RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance. Stem Cell Reports 9:1961-1975 (2017). ICC/IF ; Mouse . PubMed: 29129684
  • Szczyrba J  et al. Neuroendocrine Cells of the Prostate Derive from the Neural Crest. J Biol Chem 292:2021-2031 (2017). PubMed: 28003366
  • Robinson SC  et al. Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells. Cell Commun Signal 15:24 (2017). PubMed: 28637464
  • Stephens SB  et al. The Prohormone VGF Regulates ß Cell Function via Insulin Secretory Granule Biogenesis. Cell Rep 20:2480-2489 (2017). WB, ICC/IF . PubMed: 28877479
  • Wang Y  et al. Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells. Cell Mol Gastroenterol Hepatol 4:165-182.e7 (2017). PubMed: 29204504
  • Farrell AS  et al. MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance. Nat Commun 8:1728 (2017). PubMed: 29170413
  • Niño DF  et al. Retinoic Acid Improves Incidence and Severity of Necrotizing Enterocolitis by Lymphocyte Balance Restitution and Repopulation of LGR5+ Intestinal Stem Cells. Shock 47:22-32 (2017). PubMed: 27488085
  • Takahashi Y  et al. Reciprocal Inflammatory Signaling Between Intestinal Epithelial Cells and Adipocytes in the Absence of Immune Cells. EBioMedicine 23:34-45 (2017). PubMed: 28789943
  • Yanai H  et al. Intestinal stem cells contribute to the maturation of the neonatal small intestine and colon independently of digestive activity. Sci Rep 7:9891 (2017). PubMed: 28860595
  • Gamper I  et al. Determination of the physiological and pathological roles of E2F3 in adult tissues. Sci Rep 7:9932 (2017). PubMed: 28855541
  • Cedeno RJ  et al. The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment. PLoS One 12:e0185196 (2017). PubMed: 28934364
  • Miyoshi H  et al. Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium. EMBO J 36:5-24 (2017). PubMed: 27797821
  • Yuan H  et al. HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes. Sci Rep 7:45617 (2017). IHC-P ; Human . PubMed: 28378747
  • Saloustros E  et al. Prkar1a gene knockout in the pancreas leads to neuroendocrine tumorigenesis. Endocr Relat Cancer 24:31-40 (2017). PubMed: 27803029
  • Jadhav U  et al. Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells. Cell Stem Cell 21:65-77.e5 (2017). PubMed: 28648363
  • Yissachar N  et al. An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk. Cell 168:1135-1148.e12 (2017). PubMed: 28262351
  • Engel NW  et al. Canonical Wnt Signaling Drives Tumor-Like Lesions from Sox2-Positive Precursors of the Murine Olfactory Epithelium. PLoS One 11:e0166690 (2016). IHC-P ; Mouse . PubMed: 27902722
  • Tattoli I  et al. NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation. Cell Rep 14:2576-86 (2016). PubMed: 26971996
  • Weiss V  et al. Immunohistochemical analysis of the Wnt/ß-catenin signaling pathway in pancreatic neuroendocrine neoplasms. World J Gastrointest Oncol 8:615-22 (2016). PubMed: 27574554
  • Ravindran R  et al. The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation. Nature 531:523-7 (2016). IHC-P ; Mouse . PubMed: 26982722
  • Nakagawa A  et al. Selective and reversible suppression of intestinal stem cell differentiation by pharmacological inhibition of BET bromodomains. Sci Rep 6:20390 (2016). IHC-P ; Mouse . PubMed: 26856877
  • Fielitz K  et al. Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells. Oncotarget 7:74415-74426 (2016). IHC-P ; Mouse . PubMed: 27769070
  • Wei J  et al. Rapid progression of mixed neuroendocrine carcinoma-acinar adenocarcinoma of the prostate: A case report. Oncol Lett 12:1019-1022 (2016). IHC-P ; Human . PubMed: 27446387
  • Sui X  et al. Prostate cancer metastasis to the distal phalanx of the left hallux: The first confirmed case and literature review. Oncol Lett 12:1074-1078 (2016). IHC-P ; Human . PubMed: 27446396
  • Takada Y  et al. Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling. Development 143:3532-3539 (2016). PubMed: 27510977
  • Cao C  et al. An unusual mediastinal parathyroid carcinoma coproducing PTH and PTHrP: A case report. Oncol Lett 11:4113-4116 (2016). PubMed: 27313750
  • Watanabe N  et al. Requirement of Gaq/Ga11 Signaling in the Preservation of Mouse Intestinal Epithelial Homeostasis. Cell Mol Gastroenterol Hepatol 2:767-782.e6 (2016). PubMed: 28174748
  • Chiacchiera F  et al. PRC2 preserves intestinal progenitors and restricts secretory lineage commitment. EMBO J 35:2301-2314 (2016). IHC-P . PubMed: 27585866
  • Engevik AC  et al. The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach. Cell Mol Gastroenterol Hepatol 2:605-624 (2016). PubMed: 27990460
  • Wieck MM  et al. Human and Murine Tissue-Engineered Colon Exhibit Diverse Neuronal Subtypes and Can Be Populated by Enteric Nervous System Progenitor Cells When Donor Colon Is Aganglionic. Tissue Eng Part A 22:53-64 (2016). PubMed: 26414777
  • Schumacher MA  et al. The use of murine-derived fundic organoids in studies of gastric physiology. J Physiol 593:1809-27 (2015). Flow Cyt, IHC-P . PubMed: 25605613
  • Bertaux-Skeirik N  et al. CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation. PLoS Pathog 11:e1004663 (2015). Flow Cyt . PubMed: 25658601
  • Pierre JF  et al. The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition. Am J Physiol Gastrointest Liver Physiol 309:G431-42 (2015). PubMed: 26185331
  • Davis H  et al. Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. Nat Med 21:62-70 (2015). IHC . PubMed: 25419707
  • Simpson PD  et al. Striking Oxygen Sensitivity of the Peptidylglycine a-Amidating Monooxygenase (PAM) in Neuroendocrine Cells. J Biol Chem 290:24891-901 (2015). WB ; Human . PubMed: 26296884
  • McFarlane MR  et al. Scap is required for sterol synthesis and crypt growth in intestinal mucosa. J Lipid Res 56:1560-71 (2015). PubMed: 25896350
  • Stancikova J  et al. NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling. Cell Signal 27:245-56 (2015). IHC ; Mouse . PubMed: 25446263
  • Mogoanta SS  et al. A nonfunctional neuroendocrine tumor of the pancreas - a case report. Rom J Morphol Embryol 56:511-9 (2015). IHC ; Human . PubMed: 26193221
  • Kitajima S  et al. Undifferentiated State Induced by Rb-p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts. Stem Cells 33:1657-69 (2015). PubMed: 25694388
  • Chang PC  et al. Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells. PLoS One 9:e88556 (2014). IHC-P ; Human . PubMed: 24551118
  • Makarev E & Gorivodsky M Islet1 and its co-factor ldb1 are expressed in quiescent cells of mouse intestinal epithelium. PLoS One 9:e95256 (2014). IHC-P ; Mouse . PubMed: 24755910
  • Kober OI  et al. ?d T-cell-deficient mice show alterations in mucin expression, glycosylation, and goblet cells but maintain an intact mucus layer. Am J Physiol Gastrointest Liver Physiol 306:G582-93 (2014). ICC/IF ; Mouse . PubMed: 24503767
  • Pinheiro PS  et al. The BAR domain protein PICK1 controls vesicle number and size in adrenal chromaffin cells. J Neurosci 34:10688-700 (2014). PubMed: 25100601
  • Mounir Z  et al. TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation. Oncogene N/A:N/A (2014). PubMed: 25263440
  • Terry NA  et al. Impaired enteroendocrine development in intestinal-specific Islet1 mouse mutants causes impaired glucose homeostasis. Am J Physiol Gastrointest Liver Physiol 307:G979-91 (2014). PubMed: 25214396
  • McFarlane MR  et al. Induced ablation of ghrelin cells in adult mice does not decrease food intake, body weight, or response to high-fat diet. Cell Metab 20:54-60 (2014). PubMed: 24836560
  • Davis H  et al. Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines. Gut : (2013). PubMed: 23676439
  • König K  et al. Loss of the keratin cytoskeleton is not sufficient to induce epithelial mesenchymal transition in a novel KRAS driven sporadic lung cancer mouse model. PLoS One 8:e57996 (2013). IHC-P ; Mouse . PubMed: 23536778
  • Wrzosek L  et al. Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent. BMC Biol 11:61 (2013). WB ; Mouse, Human . PubMed: 23692866
  • Pedersen J  et al. Glucose metabolism is altered after loss of L cells and a-cells but not influenced by loss of K cells. Am J Physiol Endocrinol Metab 304:E60-73 (2013). PubMed: 23115082
  • Weisbrod AB  et al. Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors. Horm Cancer 4:165-75 (2013). IHC-P ; Human . PubMed: 23361940
  • Powell AE  et al. The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell 149:146-58 (2012). PubMed: 22464327
  • Duca FA  et al. Increased oral detection, but decreased intestinal signaling for fats in mice lacking gut microbiota. PLoS One 7:e39748 (2012). IHC . PubMed: 22768116
  • IJssennagger N  et al. Dietary haem stimulates epithelial cell turnover by downregulating feedback inhibitors of proliferation in murine colon. Gut 61:1041-9 (2012). PubMed: 21948946
  • Habib AM  et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology 153:3054-65 (2012). PubMed: 22685263
  • Hughes KR  et al. Heterogeneity in histone 2B-green fluorescent protein-retaining putative small intestinal stem cells at cell position 4 and their absence in the colon. Am J Physiol Gastrointest Liver Physiol 303:G1188-201 (2012). PubMed: 22997199
  • Konsavage WM  et al. The Myc 3' Wnt-responsive element regulates homeostasis and regeneration in the mouse intestinal tract. Mol Cell Biol 32:3891-902 (2012). PubMed: 22826434
  • Angus-Hill ML  et al. T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. Proc Natl Acad Sci U S A 108:4914-9 (2011). IHC-Fr ; Mouse . PubMed: 21383188
  • Kim TH & Shivdasani RA Notch signaling in stomach epithelial stem cell homeostasis. J Exp Med 208:677-88 (2011). PubMed: 21402740
  • Zhou D  et al. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance. Proc Natl Acad Sci U S A : (2011). PubMed: 22042863
  • Martin P  et al. Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition. Am J Pathol 179:422-35 (2011). IHC-P ; Mouse . PubMed: 21703421
  • Arnold K  et al. Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice. Cell Stem Cell 9:317-29 (2011). PubMed: 21982232
  • Chandra R  et al. Pseudopod-like basal cell processes in intestinal cholecystokinin cells. Cell Tissue Res 341:289-97 (2010). PubMed: 20582553
  • Wilson CH  et al. The activating mutation R201C in GNAS promotes intestinal tumourigenesis in Apc(Min/+) mice through activation of Wnt and ERK1/2 MAPK pathways. Oncogene 29:4567-75 (2010). PubMed: 20531296
  • Duckworth CA & Pritchard DM Suppression of apoptosis, crypt hyperplasia, and altered differentiation in the colonic epithelia of bak-null mice. Gastroenterology 136:943-52 (2009). IHC-P ; Mouse . PubMed: 19185578
  • Begus-Nahrmann Y  et al. p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice. Nat Genet 41:1138-43 (2009). IHC-P ; Mouse . PubMed: 19718028
  • Jeon TI  et al. SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice. J Clin Invest 118:3693-700 (2008). IHC-P ; Mouse . PubMed: 18846256
  • Haigis K  et al. The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium. J Biol Chem 281:638-47 (2006). PubMed: 16258171

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