製品の概要
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製品名Anti-Chemokine Receptor D6 antibody
Chemokine Receptor D6 一次抗体 製品一覧 -
製品の詳細Goat polyclonal to Chemokine Receptor D6
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由来種Goat
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特異性Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region.
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アプリケーション適用あり: Flow Cyt, ICC, IHC-P, ELISAmore details
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種交差性交差種: Mouse
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免疫原
Synthetic peptide:
SSSIYDYDYLDDMTILVCRKDEVLSFGRC
, corresponding to amino acids 18-45 of Mouse Chemokine Receptor D6 -
ポジティブ･コントロール
- Mouse spleen cells or lung.
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特記事項
Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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バッファーPreservative: 0.1% Sodium azide
Constituent: 0.1% BSA -
Concentration information loading... -
精製度Immunogen affinity purified
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一次抗体 備考Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab1656 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
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| Flow Cyt | Use at an assay dependent concentration. 1-3µl/106cells/50-100µl.
ab37373 - Goat polyclonal IgG, is suitable for use as an isotype control with this antibody.
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| ICC | 1/500. | |
| IHC-P | 1/250. | |
| ELISA | 1/100000. |
ターゲット情報
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機能Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3.
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組織特異性Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors.
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配列類似性Belongs to the G-protein coupled receptor 1 family.
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細胞内局在Cell membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 59289 Mouse
- SwissProt: O08707 Mouse
- Unigene: 258105 Mouse
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別名
- C C chemokine receptor D6 antibody
- C-C chemokine receptor D6 antibody
- CC chemokine binding receptor JAB61 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse spleen section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse lung section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse spleen section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
プロトコール
参考文献
This product has been referenced in:
- Hajrasouliha AR et al. Expression of the chemokine decoy receptor D6 mediates dendritic cell function and promotes corneal allograft rejection. Mol Vis 19:2517-25 (2013). Flow Cyt ; Mouse . Read more (PubMed: 24357920) »
- Besusso D et al. BDNF-TrkB signaling in striatopallidal neurons controls inhibition of locomotor behavior. Nat Commun 4:2031 (2013). IHC . Read more (PubMed: 23774276) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"