Anti-Chemokine Receptor D6 抗体 (ab1656)
Key features and details
- Goat polyclonal to Chemokine Receptor D6
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-Chemokine Receptor D6 antibody
Chemokine Receptor D6 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Chemokine Receptor D6 -
由来種
Goat -
特異性
Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse -
免疫原
Synthetic peptide:
SSSIYDYDYLDDMTILVCRKDEVLSFGRC
, corresponding to amino acids 18-45 of Mouse Chemokine Receptor D6 -
ポジティブ・コントロール
- Mouse spleen cells or lung.
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特記事項
Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
一次抗体 備考
Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab1656 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
アプリケーション | Abreviews | 特記事項 |
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IHC-P | 1/250. |
ターゲット情報
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機能
Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3. -
組織特異性
Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 59289 Mouse
- SwissProt: O08707 Mouse
- Unigene: 258105 Mouse
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別名
- C C chemokine receptor D6 antibody
- C-C chemokine receptor D6 antibody
- CC chemokine binding receptor JAB61 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse spleen section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse lung section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse spleen section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
プロトコール
参考文献 (4)
ab1656 は 4 報の論文で使用されています。
- Hajrasouliha AR et al. Expression of the chemokine decoy receptor D6 mediates dendritic cell function and promotes corneal allograft rejection. Mol Vis 19:2517-25 (2013). Flow Cyt ; Mouse . PubMed: 24357920
- Besusso D et al. BDNF-TrkB signaling in striatopallidal neurons controls inhibition of locomotor behavior. Nat Commun 4:2031 (2013). IHC . PubMed: 23774276
- Wang B et al. Dlx6 regulates molecular properties of the striatum and central nucleus of the amygdala. J Comp Neurol 519:2320-34 (2011). PubMed: 21452241
- Kin NW et al. DNA Microarray Gene Expression Profile of Marginal Zone versus Follicular B Cells and Idiotype Positive Marginal Zone B Cells before and after Immunization with Streptococcus pneumoniae. J Immunol 180:6663-74 (2008). WB, Flow Cyt ; Mouse . PubMed: 18453586