CGP 7930, Positive allosteric modulator of GABAB receptors (ab120492)

製品の概要

  • 製品名

    CGP 7930, Positive allosteric modulator of GABAB receptors
  • 製品の詳細

    Positive GABAB receptor allosteric modulator
  • 生理活性の詳細

    Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen (ab120325).
  • 精製度

    > 98%
  • CAS 番号

    57717-80-3
  • 構造式

    Chemical Structure

製品の特性

関連製品

参考文献

This product has been referenced in:

  • Adams CL & Lawrence AJ CGP7930: a positive allosteric modulator of the GABAB receptor. CNS Drug Rev 13:308-16 (2007). Read more (PubMed: 17894647) »
  • Chen Y  et al. GABA(B) receptor modulators potentiate baclofen-induced depression of dopamine neuron activity in the rat ventral tegmental area. Br J Pharmacol 144:926-32 (2005). Read more (PubMed: 15711597) »
  • Carai MA  et al. In vivo effectiveness of CGP7930, a positive allosteric modulator of the GABAB receptor. Eur J Pharmacol 504:213-6 (2004). Read more (PubMed: 15541424) »

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