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リコンビナントRabMAb

Anti-Cdc37 抗体 [EPR4935] (ab108305)

Submit a review Submit a question References (1)
Western blot - Anti-Cdc37 antibody [EPR4935] (ab108305)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cdc37 antibody [EPR4935] (ab108305)
  • Anti-Cdc37 antibody [EPR4935] (ab108305)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR4935] to Cdc37
  • Suitable for: WB, IHC-P
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Alexa Fluor® 488 Carrier Free

製品の概要

  • 製品名

    Anti-Cdc37 antibody [EPR4935]
    Cdc37 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR4935] to Cdc37

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WB, IHC-Pmore details

  • 種交差性

    交差種: Human

  • 免疫原

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • ポジティブ･コントロール

    • K562 cell lysate, Jurkat cell lysate, LnCaP cell lysate, SW480 cell lysate, human brain tissue

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab108305の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/50000 - 1/200000. Predicted molecular weight: 44 kDa.
IHC-P
1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

perform antigen retrieval
特記事項
WB
1/50000 - 1/200000. Predicted molecular weight: 44 kDa.
IHC-P
1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

perform antigen retrieval

ターゲット情報

  • 機能

    Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.

  • 配列類似性

    Belongs to the CDC37 family.

  • 翻訳後修飾

    Constitutively sumoylated by UBE2I.

  • 細胞内局在

    Cytoplasm.
  • Information by UniProt

  • 参照データベース

    • 別名

      • CDC 37 antibody
      • Cdc37 antibody
      • CDC37 cell division cycle 37 homolog antibody
      • CDC37 cell division cycle 37 S cerevisiae homolog antibody
      • CDC37 cell division cycle 37, S cerevisiae, homolog of antibody
      • Cdc37 homolog antibody
      • CDC37 protein antibody
      • CDC37_HUMAN antibody
      • CDC37A antibody
      • cell division cycle 37 antibody
      • Cell division cycle 37 homolog antibody
      • Hsp90 chaperone protein kinase targeting subunit antibody
      • Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody
      • Hsp90 chaperone protein kinase-targeting subunit antibody
      • Hsp90 co chaperone Cdc37 antibody
      • Hsp90 co-chaperone Cdc37 antibody
      • p50 antibody
      • p50Cdc37 antibody
      • S cerevisiae hypothetical protein CDC37 antibody
      see all

    画像

    • Western blot - Anti-Cdc37 antibody [EPR4935] (ab108305)
      Western blot - Anti-Cdc37 antibody [EPR4935] (ab108305)
      All lanes : Anti-Cdc37 antibody [EPR4935] (ab108305) at 1/50000 dilution

      Lane 1 : K562 cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : LnCaP cell lysate
      Lane 4 : SW480 cell lysate

      Lysates/proteins at 10 µg per lane.

      Performed under reducing conditions.

      Predicted band size: 44 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cdc37 antibody [EPR4935] (ab108305)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cdc37 antibody [EPR4935] (ab108305)

      ab108305, at 1/250, staining Cdc37 in human brain tissue by immunohistochemistry.

      Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    • Anti-Cdc37 antibody [EPR4935] (ab108305)
      Anti-Cdc37 antibody [EPR4935] (ab108305)

    参考文献 (1)

    ab108305 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab108305 は 1 報の論文で使用されています。

    • Tirosh O  et al. The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions. PLoS Pathog 11:e1005288 (2015). WB . PubMed: 26599541

    レビューと Q&A

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