Anti-CD8 alpha 抗体 [IBL-3/25] (ab3081)
![Flow Cytometry - Anti-CD8 alpha antibody [IBL-3/25] (ab3081)](https://www.abcam.co.jp/ps/products/3/ab3081/Images/ab3081-469632-anticd8-alpha-antibody-ibl3-25-flow-cytometry.jpg "Flow Cytometry - Anti-CD8 alpha antibody [IBL-3/25] (ab3081)")
Key features and details
- Rat monoclonal [IBL-3/25] to CD8 alpha
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Isotype: IgG1
製品の概要
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製品名
Anti-CD8 alpha antibody [IBL-3/25]
CD8 alpha 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [IBL-3/25] to CD8 alpha -
由来種
Rat -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse CD8 alpha. Mouse spleen cells.
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ポジティブ･コントロール
- Flow Cyt: mouse peripheral lymph node
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
IBL-3/25 -
ミエローマ
Sp2/0-Ag14 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab3081の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use a concentration of 5 µg/ml.
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| 特記事項 |
|---|
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Flow Cyt
Use a concentration of 5 µg/ml. |
ターゲット情報
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機能
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. -
関連疾患
Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. -
配列類似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻訳後修飾
All of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 12525 Mouse
- SwissProt: P01731 Mouse
- Unigene: 1858 Mouse
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別名
- alpha polypeptide (p32) antibody
- CD_antigen=CD8a antibody
- CD8 antibody
see all
画像
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Flow Cytometry - Anti-CD8 alpha antibody [IBL-3/25] (ab3081)
Flow cytometry analysis of mouse peripheral lymph node labeling CD8 alpha with ab3081 at 5ug/mL.
PE-conjugated anti-rat IgG
Red line: isotype control labeling with <3% positive events
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab3081 は 4 報の論文で使用されています。
- Draghiciu O et al. Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication. Oncoimmunology 4:e989764 (2015). IHC ; Mouse . PubMed: 25949902
- Gao X et al. Role of donor and host cells in muscle-derived stem cell-mediated bone repair: differentiation vs. paracrine effects. FASEB J 28:3792-809 (2014). PubMed: 24843069
- Kersting S et al. The impact of JNK inhibitor D-JNKI-1 in a murine model of chronic colitis induced by dextran sulfate sodium. J Inflamm Res 6:71-81 (2013). IHC-FoFr ; Mouse . PubMed: 23667316
- Kotakadi VS et al. Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. Carcinogenesis 29:1799-806 (2008). IHC-P ; Mouse . PubMed: 18567620