Anti-CD38 抗体 [FS02] (ab1260)

I can confirm that ab1260 is not the agonistic monoclonal antibody (IB4) stated in the literature and unfortunately, we do not have this product in the catalogue. ab1260 has the clone number FS02 instead of IB4 and we have no information regarding whether it is an agonistic monoclonal antibody.

Thank you for your enquiry.

Having contacted the originators of these antibodies, we can let you know the following about the immunogens:

ab2577: Tissue / cell preparation (Human thymocytes in foetus). According to our information the epitope mapping was not done. Only its location to the extracellular portion of the protein is known.

ab93941: Purified recombinant fragment of Human CD38 expressed in E. coli.The peptide maps between amino acids 171 and 292.

ab108403: A synthetic peptide corresponding to residues on the C terminus of Human CD38. The peptide maps between amino acids 275 and 300, on the C-terminus of human CD38 (UniProt: P28907).

ab49644: Recombinant fusion protein corresponding to the extracellular region of human CD38 molecule. Unfortunately, futher details of this immunogen sequence are not available.

ab1260: I am sorry but we do know the immunogen sequence or the range of amino acids or the region of the peptide from which it is derived. The producer of the hybridoma did not give us this kind of information.

ab34283: The details of the immunogen for this antibody are also not available.

ab75231: The antibody, CD 38 was raised to a prokaryotic recombinant protein corresponding to the extracellular region of the CD38 molecule. This region corresponds to amino acids 45-300. Unfortunately, the antibody has not been epitope mapped in order to determine the exact amino acid sequence to which it binds.

ab91390: This monoclonal was development using as immunogen whole cell of human acute lymphoblastic B leukaemia. The antibody has also not been epitope mapped.

ab9504: Nawalma cell line. The antibody has also not been epitope mapped.

We aim to provide as much information as possible to customers, so I am sorry that this has not entirely been possible on this occasion. I hope this information is nevertheless helpful to you. Please do not hesitate to contact us if you need any more advice or information, or if we could be of any help in choosing the most suitable antibody for your experimental layout.

Thank you for your email. Ab1260 has been used in the following two publications, please refer to them for more information regarding this antibody: Morra M et al. CD38 is functionally dependent on the TCR/CD3 complex in human T cells. FASEB J 12:581-92 (1998). PubMed: 9576485 Zupo S et al. CD38 signaling by agonistic monoclonal antibody prevents apoptosis of human germinal center B cells. Eur J Immunol 24:1218-22 (1994). PubMed: 8181532