Anti-CD3 抗体 [UCH-T1] (ab22)
製品の概要
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製品名Anti-CD3 antibody [UCH-T1]
CD3 一次抗体 製品一覧 -
製品の詳細Mouse monoclonal [UCH-T1] to CD3
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由来種Mouse
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アプリケーション適用あり: Flow Cyt, IP, RIA, IHC-Frmore details
適用なし: IHC-P -
種交差性交差種: Human
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免疫原
Human infant thymocytes and Sezary cells
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エピトープEpsilon-chain
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特記事項Use: Enrichment of T cell populations by cell sorting or panning.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Concentration information loading... -
精製度Protein A purified
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ポリ/モノモノクローナル
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クローン名UCH-T1
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ミエローマP3-NS1/1-Ag4-1
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アイソタイプIgG1
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軽鎖の種類kappa
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研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab22 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt | Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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| IP | Use at an assay dependent concentration. | |
| RIA | Use at an assay dependent concentration. | |
| IHC-Fr | Use at an assay dependent concentration. |
追加情報
Is unsuitable for IHC-P.
ターゲット情報
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機能The CD3 complex mediates signal transduction.
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関連疾患Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.
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配列類似性Contains 1 ITAM domain.
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細胞内局在Membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 915 Human
- Entrez Gene: 916 Human
- Entrez Gene: 917 Human
- Entrez Gene: 919 Human
- Omim: 186740 Human
- Omim: 186780 Human
- Omim: 186790 Human
- Omim: 186830 Human
see all -
別名
- 4930549J05Rik antibody
- A430104F18Rik antibody
- AW552088 antibody
see all
データシートおよび資料
参考文献
This product has been referenced in:
- Beverley PC & Callard RE Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. Eur J Immunol 11:329-34 (1981). Read more (PubMed: 6788570) »
