Anti-CD14 抗体 [UCHM1] (ab6623)
Key features and details
- Mouse monoclonal [UCHM1] to CD14
- Suitable for: Flow Cyt
- Reacts with: Human, Cynomolgus monkey, Rhesus monkey
- Isotype: IgG2a
製品の概要
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製品名
Anti-CD14 antibody [UCHM1]
CD14 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [UCHM1] to CD14 -
由来種
Mouse -
特異性
ab6623 recognises a monocyte surface antigen of 55 kDa found chiefly on monocytes. UCHM1 was clustered at the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens. Oxford 1986, as CDw14, group A. In tonsil tissue sections UCHM1 gives positive staining reactions with monocytic cells, the interfollicular tissue macrophages seen under the capsule, and dendritic reticulum cells. Skin Langerhans cells are always negative. UCHM1 also reacts with Kupffer cells and sinus lining cells on the liver. -
アプリケーション
適用あり: Flow Cytmore details
適用なし: IHC-P -
種交差性
交差種: Human, Cynomolgus monkey, Rhesus monkey -
免疫原
Human Thymocytes followed by peripheral blood mononuclear cells
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ポジティブ・コントロール
- Tonsil.
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特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.60
Preservative: 0.09% Sodium azide -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
UCHM1 -
ミエローマ
NS1/1-Ag4-1 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
Our Abpromise guarantee covers the use of ab6623 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt | Use at an assay dependent concentration. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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ターゲット情報
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機能
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. -
組織特異性
Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. -
配列類似性
Contains 11 LRR (leucine-rich) repeats. -
翻訳後修飾
N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 929 Human
- Omim: 158120 Human
- SwissProt: P08571 Human
- Unigene: 163867 Human
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別名
- CD 14 antibody
- CD_antigen=CD14 antibody
- CD14 antibody
see all
画像
プロトコール
データシートおよび資料
参考文献 (0)
ab6623 は論文での使用が確認できていません。