Anti-CD14 抗体 [UCHM1] (ab6623)

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Key features and details

  • Mouse monoclonal [UCHM1] to CD14
  • Suitable for: Flow Cyt
  • Reacts with: Human, Cynomolgus monkey, Rhesus monkey
  • Isotype: IgG2a

製品の概要

  • 製品名

    Anti-CD14 antibody [UCHM1]
    CD14 一次抗体 製品一覧

  • 製品の詳細

    Mouse monoclonal [UCHM1] to CD14

  • 由来種

    Mouse

  • 特異性

    ab6623 recognises a monocyte surface antigen of 55 kDa found chiefly on monocytes. UCHM1 was clustered at the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens. Oxford 1986, as CDw14, group A. In tonsil tissue sections UCHM1 gives positive staining reactions with monocytic cells, the interfollicular tissue macrophages seen under the capsule, and dendritic reticulum cells. Skin Langerhans cells are always negative. UCHM1 also reacts with Kupffer cells and sinus lining cells on the liver.

  • アプリケーション

    適用あり: Flow Cytmore details
    適用なし: IHC-P

  • 種交差性

    交差種: Human, Cynomolgus monkey, Rhesus monkey

  • 免疫原

    Human Thymocytes followed by peripheral blood mononuclear cells

  • ポジティブ･コントロール

    • Tonsil.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab6623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use at an assay dependent concentration.

ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

 
  • 追加情報
    Is unsuitable for IHC-P.

    • ターゲット情報

    • 機能

      Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

    • 組織特異性

      Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.

    • 配列類似性

      Contains 11 LRR (leucine-rich) repeats.

    • 翻訳後修飾

      N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.

    • 細胞内局在

      Cell membrane.
    • Information by UniProt

    • 参照データベース

      • 別名

        • CD 14 antibody
        • CD_antigen=CD14 antibody
        • CD14 antibody
        • CD14 antigen antibody
        • CD14 molecule antibody
        • CD14_HUMAN antibody
        • LPS-R antibody
        • Mo2 antibody
        • Monocyte differentiation antigen CD14 antibody
        • Monocyte differentiation antigen CD14 urinary form antibody
        • Monocyte differentiation antigen CD14, membrane-bound form antibody
        • Myeloid cell specific leucine rich glycoprotein antibody
        • Myeloid cell-specific leucine-rich glycoprotein antibody
        see all

      画像

      • Flow Cytometry - Anti-CD14 antibody [UCHM1] (ab6623)
        Flow Cytometry - Anti-CD14 antibody [UCHM1] (ab6623)
        ab6623 staining of human peripheral blood monocytes, visualised with rabbit anti-mouse IgG: FITC.

      参考文献 (0)

      ab6623 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab6623 は論文での使用が確認できていません。

      レビューと Q&A

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      レビューを送る 質問を送る

      Question

      Can this antibody be used with paraffin sections or only frozen as stated on the datasheet?

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      Answer

      This antibody has been tested on paraffin sections and does not work. In IHC, it is known to work only with frozen sections.

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