Key features and details
- Mouse monoclonal [UCHM1] to CD14
- Suitable for: Flow Cyt
- Reacts with: Human, Cynomolgus monkey, Rhesus monkey
- Isotype: IgG2a
製品名Anti-CD14 antibody [UCHM1]
CD14 一次抗体 製品一覧
製品の詳細Mouse monoclonal [UCHM1] to CD14
特異性ab6623 recognises a monocyte surface antigen of 55 kDa found chiefly on monocytes. UCHM1 was clustered at the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens. Oxford 1986, as CDw14, group A. In tonsil tissue sections UCHM1 gives positive staining reactions with monocytic cells, the interfollicular tissue macrophages seen under the capsule, and dendritic reticulum cells. Skin Langerhans cells are always negative. UCHM1 also reacts with Kupffer cells and sinus lining cells on the liver.
アプリケーション適用あり: Flow Cytmore details
種交差性交差種: Human, Cynomolgus monkey, Rhesus monkey
Human Thymocytes followed by peripheral blood mononuclear cells
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Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.09% Sodium azide
Concentration information loading...
精製度Protein G purified
特記事項（精製）Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Our Abpromise guarantee covers the use of ab6623 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
機能Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
組織特異性Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
配列類似性Contains 11 LRR (leucine-rich) repeats.
翻訳後修飾N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
- Information by UniProt
- CD 14 antibody
- CD_antigen=CD14 antibody
- CD14 antibody