Biotin Anti-CD13 抗体 [WM15] (ab130430)
Key features and details
- Biotin Mouse monoclonal [WM15] to CD13
- Suitable for: Flow Cyt
- Reacts with: Human, Non human primates
- Conjugation: Biotin
- Isotype: IgG1
製品の概要
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製品名
Biotin Anti-CD13 antibody [WM15]
CD13 一次抗体 製品一覧 -
製品の詳細
Biotin Mouse monoclonal [WM15] to CD13 -
由来種
Mouse -
標識
Biotin -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human, Non human primates -
免疫原
Tissue, cells or virus corresponding to Human CD13. Human AML cells.
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ポジティブ・コントロール
- Flow Cyt: human peripheral blood
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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精製度
Size exclusion -
ポリ/モノ
モノクローナル -
クローン名
WM15 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
- PerCP/Cy5.5® Anti-CD13 antibody [WM15] (ab157316)
- Alexa Fluor® 488 Anti-CD13 antibody [WM15] (ab239271)
- APC Anti-CD13 antibody [WM15] (ab239295)
- PE/DyLight™ 594 Anti-CD13 antibody [WM15] (ab239330)
- Anti-CD13 antibody [WM15] - BSA and Azide free (ab252261)
- FITC Anti-CD13 antibody [WM15] (ab52461)
- PE Anti-CD13 antibody [WM15], prediluted (ab69775)
- Anti-CD13 antibody [WM15] (ab7417)
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab130430の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use a concentration of 3 - 5 µg/ml.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use a concentration of 3 - 5 µg/ml. ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types including small intestinal and tubular epithelial cells, macrophages, granulocytes and synaptic membranes from the CNS. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection. -
組織特異性
Expressed in epithelial cells of the kidney, intestine, and respiratory tract; granulocytes, monocytes, fibroblasts, endothelial cells, cerebral pericytes at the blood-brain barrier, synaptic membranes of cells in the CNS. Also expressed in endometrial stromal cells, but not in the endometrial glandular cells. Found in the vasculature of tissues that undergo angiogenesis and in malignant gliomas and lymph node metastases from multiple tumor types but not in blood vessels of normal tissues. A soluble form has been found in plasma. It is found to be elevated in plasma and effusions of cancer patients. -
配列類似性
Belongs to the peptidase M1 family. -
ドメイン
Amino acids 260-353 are essential to mediate susceptibility to infection with HCoV-229E (in porcine/human chimeric studies) and more specifically amino acids 288-295 (mutagenesis studies). -
翻訳後修飾
Sulfated.
N- and O-glycosylated.
May undergo proteolysis and give rise to a soluble form. -
細胞内局在
Cell membrane. Cytoplasm > cytosol. A soluble form has also been detected. - Information by UniProt
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参照データベース
- Entrez Gene: 290 Human
- Omim: 151530 Human
- SwissProt: P15144 Human
- Unigene: 1239 Human
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別名
- Alanyl (membrane) aminopeptidase antibody
- Alanyl aminopeptidase antibody
- Aminopeptidase M antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab130430 は論文での使用が確認できていません。