Anti-CD11c 抗体 [FK24] (ab23602)
Key features and details
- Mouse monoclonal [FK24] to CD11c
- Suitable for: ICC, ICC/IF
- Reacts with: Human
- Isotype: IgG1
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-CD11c antibody [FK24]
CD11c 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [FK24] to CD11c -
由来種
Mouse -
アプリケーション
適用あり: ICC, ICC/IFmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human CD11c.
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特記事項
ab23602 can be used for the identification of CD11c-positive cells using immunoperoxidase procedures. It can thus be used for the identification of monocytes and granylocytes using immunoperoxidase procedures. In addition it seems useful for identification of myelomonocytic and monocytic leukemias.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.3
Constituent: Ascites -
Concentration information loading... -
精製度
Protein A purified -
一次抗体 備考
ab23602 can be used for the identification of CD11c-positive cells using immunofluorescence or immunoperoxidase procedures. It can thus be used for the identification of monocytes and granylocytes using either immunofluorescence or immunoperoxidase procedures. In addition it seems useful for identification of myelomonocytic and monocytic leukemias. -
ポリ/モノ
モノクローナル -
クローン名
FK24 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab23602の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC |
Use at an assay dependent concentration.
Dilute antibody preferably in PBS plus 1% BSA and 0.01% Na-azide. |
|
| ICC/IF | (1) |
Use at an assay dependent concentration.
Dilute antibody preferably in PBS plus 1% BSA and 0.01% Na-azide. |
| 特記事項 |
|---|
|
ICC
Use at an assay dependent concentration. Dilute antibody preferably in PBS plus 1% BSA and 0.01% Na-azide. |
|
ICC/IF
Use at an assay dependent concentration. Dilute antibody preferably in PBS plus 1% BSA and 0.01% Na-azide. |
ターゲット情報
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機能
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. -
組織特異性
Predominantly expressed in monocytes and granulocytes. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
ドメイン
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3687 Human
- Omim: 151510 Human
- SwissProt: P20702 Human
- Unigene: 248472 Human
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別名
- 95 alpha chain antibody
- 95 antibody
- CD 11c antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (1)
ab23602 は 1 報の論文で使用されています。
- Rane JK et al. Conserved two-step regulatory mechanism of human epithelial differentiation. Stem Cell Reports 2:180-8 (2014). ICC/IF ; Human . PubMed: 24527392
