製品の概要

  • 製品名
    Anti-CCR6 antibody
    CCR6 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to CCR6
  • 由来種
    Goat
  • アプリケーション
    適用あり: IHC-Fr, ELISA, ICC, IHC-Pmore details
  • 種交差性
    交差種: Human
    非交差種: Mouse
  • 免疫原

    Synthetic peptide:

    YFVSVNTSYYSVDSEMLLCSLQEVRQFSR

    , corresponding to amino acids 18-46 of Human CCR6.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • ポジティブ･コントロール
    • Human spleen or peripheral blood

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab1659 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr 1/250. PubMed: 19095953
ELISA 1/75000.
ICC 1/300.
IHC-P 1/250.

ターゲット情報

  • 機能
    Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.
  • 組織特異性
    Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
    • 別名
      • BN 1 antibody
      • BN1 antibody
      • C C chemokine receptor type 6 antibody
      • C C CKR 6 antibody
      • C-C chemokine receptor type 6 antibody
      • C-C CKR-6 antibody
      • CC chemokine receptor type 6 antibody
      • CC CKR 6 antibody
      • CC R6 antibody
      • CC-CKR-6 antibody
      • CCCKR6 antibody
      • CCR 6 antibody
      • CCR-6 antibody
      • Ccr6 antibody
      • CCR6_HUMAN antibody
      • CD 196 antibody
      • CD196 antibody
      • CD196 antigen antibody
      • Chemokine (C C motif) receptor 6 antibody
      • Chemokine (C C) receptor 6 antibody
      • Chemokine (CC motif) receptor 6 antibody
      • Chemokine (CC) receptor 6 antibody
      • Chemokine receptor 6 antibody
      • Chemokine receptor like 3 antibody
      • Chemokine receptor-like 3 antibody
      • CKR 6 antibody
      • CKR L3 antibody
      • CKR-L3 antibody
      • CKR6 antibody
      • CKRL3 antibody
      • CMKBR 6 antibody
      • CMKBR6 antibody
      • DCR 2 antibody
      • DCR2 antibody
      • DRY 6 antibody
      • DRY6 antibody
      • G protein coupled receptor 29 antibody
      • G-protein coupled receptor 29 antibody
      • GPR 29 antibody
      • GPR CY4 antibody
      • GPR-CY4 antibody
      • GPR29 antibody
      • GPRCY 4 antibody
      • GPRCY4 antibody
      • LARC receptor antibody
      • Seven transmembrane receptor lymphocyte 22 antibody
      • STRL 22 antibody
      • STRL22 antibody
      see all

    画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR6 antibody (ab1659)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR6 antibody (ab1659)
      Immunohistochemistry on paraffin section of human spleen, at 1/250 dilution.

    参考文献

    This product has been referenced in:
    • Salim SY  et al. CD83+CCR7- dendritic cells accumulate in the subepithelial dome and internalize translocated Escherichia coli HB101 in the Peyer's patches of ileal Crohn's disease. Am J Pathol 174:82-90 (2009). IHC-Fr ; Human . Read more (PubMed: 19095953) »

    See 1 Publication for this product

    ab1659 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    レビューと Q&A

    レビューを送る 質問を送る

    3 reviews or Q&A

    10
    Votes: Highest First

    Please recommend a negative control for this antibody.

    I was informed that the best negative control is affinity purified goat IgG antibody to a protein that is not expressed on the target cells cells/tissues to be examined. For example affinity purified Goat IgG antibody to Trail-2 or Trail-3 receptor ant...

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    What is the molecular weight of this ab?

    Thank you for your enquiry. The molecular weight of this antibody is 425kDa. Please contact us again if you require further information.

    I have recently purchased this antibody from you based on your information sheet. It states that the antibody cross reacts with mouse CCR6. My Western was negative, so I looked into why this could be. I referred to the paper you cited as using the an...

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    The source of ab1659 has replied to me the following: "We agree with the customer that antibody to human CCR6 should not react with the mouse CCR6 because of the significant sequence differences. However, work with mouse white bloods cells showed c...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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