Anti-CCR3 抗体 (ab1667)
Key features and details
- Goat polyclonal to CCR3
- Suitable for: ICC
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CCR3 antibody
CCR3 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to CCR3 -
由来種
Goat -
特異性
Peptide sequence is < 50 % identical to other human chemokine receptors in this region. -
アプリケーション
適用あり: ICCmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human CCR3 aa 7-34 (N terminal).
Sequence:CVETFGTTSYYDDVGLLCEKADTRALMA
Database link: P51677 -
特記事項
Human CCR 3 is a receptor for CC chemokine eotaxin-1 and eotaxin-2. CCR 3 is constitutively expressed on eosinophils, small intestine and colon. The human CCR 3 protein contains 356 amino acids.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.1% Sodium azide
Constituents: 0.1% BSA, 0.11% Dibasic monohydrogen potassium phosphate, 0.05% Monobasic dihydrogen potassium phosphate, 0.82% Sodium chloride -
Concentration information loading...
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精製度
Immunogen affinity purified -
一次抗体 備考
Human CCR 3 is a receptor for CC chemokine eotaxin-1 and eotaxin-2. CCR 3 is constitutively expressed on eosinophils, small intestine and colon. The human CCR 3 protein contains 356 amino acids. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab1667 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ICC | 1/150. |
ターゲット情報
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機能
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. -
組織特異性
In eosinophils as well as trace amounts in neutrophils and monocytes. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1232 Human
- Omim: 601268 Human
- SwissProt: P51677 Human
- Unigene: 506190 Human
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別名
- B chemokine receptor antibody
- b-chemokine receptor antibody
- C C chemokine receptor type 3 antibody
see all
画像
プロトコール
参考文献 (19)
ab1667 は 19 報の論文で使用されています。
- Venugopal N et al. The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts. BMC Mol Cell Biol 21:25 (2020). PubMed: 32293249
- Jäger K et al. Expression of Neural Crest Markers GLDC and ERRFI1 is Correlated with Melanoma Prognosis. Cancers (Basel) 11:N/A (2019). PubMed: 30641895
- Saito Y et al. Synbiotics suppress colitis-induced tumorigenesis in a colon-specific cancer mouse model. PLoS One 14:e0216393 (2019). PubMed: 31242213
- Han Y et al. IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from ?d T Cells. Cell Rep 27:835-846.e5 (2019). PubMed: 30995480
- Shoemaker RH et al. Evaluation of the STAT3 inhibitor GLG-302 for the prevention of estrogen receptor-positive and -negative mammary cancers. Oncol Rep 42:1205-1213 (2019). PubMed: 31322250