Anti-CCR1 抗体 (ab13240)
Key features and details
- Goat polyclonal to CCR1
- Suitable for: ELISA, ICC, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CCR1 antibody
CCR1 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to CCR1 -
由来種
Goat -
特異性
Peptide sequence is < 50 % identical to other chemokine receptors in this region. -
アプリケーション
適用あり: ELISA, ICC, WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Macaque monkey
非交差種:
Mouse -
免疫原
Synthetic peptide corresponding to Human CCR1 aa 7-24 (N terminal).
Sequence:TEDYDTTTEFDYGDATPC
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ポジティブ･コントロール
- Immunocytochemistry on human peripheral blood leukocytes.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.1% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab13240の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
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| ICC |
Use at an assay dependent concentration.
|
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| WB |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
|
ELISA
Use at an assay dependent concentration. |
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ICC
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. -
組織特異性
Widely expressed in different hematopoietic cells. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1230 Human
- Entrez Gene: 574188 Macaque monkey
- Omim: 601159 Human
- SwissProt: P32246 Human
- Unigene: 301921 Human
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別名
- C C chemokine receptor type 1 antibody
- C C CKR 1 antibody
- C-C chemokine receptor type 1 antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab13240 は 1 報の論文で使用されています。
- Sheng H et al. Knockdown of FOXP1 promotes the development of lung adenocarcinoma. Cancer Biol Ther 20:537-545 (2019). PubMed: 30409062