Anti-CCL18 抗体 (ab9849)
Key features and details
- Rabbit polyclonal to CCL18
- Suitable for: ELISA, Neutralising, Sandwich ELISA, WB
- Reacts with: Human
- Isotype: unknown
製品の概要
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製品名
Anti-CCL18 antibody
CCL18 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CCL18 -
由来種
Rabbit -
アプリケーション
適用あり: ELISA, Neutralising, Sandwich ELISA, WBmore details -
種交差性
交差種: Human -
免疫原
Full length protein corresponding to CCL18.
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ポジティブ・コントロール
- Recombinant human CCL18 protein (ab9850) can be used as a positive control in WB.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute with 200µl of sterile water. -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
No preservative, sterile filtered -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
unknown -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab9849の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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Neutralising |
Use at an assay dependent concentration.
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Sandwich ELISA |
Use at an assay dependent concentration.
To detect CCL18 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with an appropriate detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant CCL18. . |
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WB |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
Neutralising
Use at an assay dependent concentration. |
Sandwich ELISA
Use at an assay dependent concentration. To detect CCL18 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with an appropriate detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant CCL18. . |
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. -
組織特異性
Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. -
配列類似性
Belongs to the intercrine beta (chemokine CC) family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 6362 Human
- Omim: 603757 Human
- SwissProt: P55774 Human
- Unigene: 143961 Human
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別名
- Alternative macrophage activation associated CC chemokine 1 antibody
- Alternative macrophage activation-associated CC chemokine 1 antibody
- AMAC-1 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (4)
ab9849 は 4 報の論文で使用されています。
- Su S et al. Blocking the recruitment of naive CD4(+) T cells reverses immunosuppression in breast cancer. Cell Res 27:461-482 (2017). Blocking ; Human . PubMed: 28290464
- Huang D et al. Epstein-Barr Virus-Induced VEGF and GM-CSF Drive Nasopharyngeal Carcinoma Metastasis via Recruitment and Activation of Macrophages. Cancer Res 77:3591-3604 (2017). PubMed: 28484077
- Nie Y et al. Tumor-Associated Macrophages Promote Malignant Progression of Breast Phyllodes Tumors by Inducing Myofibroblast Differentiation. Cancer Res 77:3605-3618 (2017). PubMed: 28512246
- Su S et al. A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis. Cancer Cell 25:605-20 (2014). PubMed: 24823638