Anti-Cardiac Troponin I 抗体 (ab231064)
Key features and details
- Rabbit polyclonal to Cardiac Troponin I
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Pig
- Isotype: IgG
製品の概要
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製品名
Anti-Cardiac Troponin I antibody
Cardiac Troponin I 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Cardiac Troponin I -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Mouse, Pig
交差が予測される動物種: Rat, Rabbit, Horse, Cow, Cat, Dog, Human -
免疫原
Recombinant full length protein (His-T7-tag) corresponding to Pig Cardiac Troponin I aa 1 to the C-terminus. Expressed in E.coli.
Database link: A5X497 -
ポジティブ・コントロール
- WB: Recombinant pig Cardiac Troponin I; mouse skeletal muscle and heart tissue lysates; pig skeletal muscle and heart lysates. IHC-P : Pig tongue and heart tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 44.12% PBS, 55.77% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Protein A purified -
特記事項(精製)
Antigen-specific affinity chromatography followed by Protein A affinity chromatography -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab231064の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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WB |
Use a concentration of 0.2 - 2 µg/ml.
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特記事項 |
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IHC-P
Use a concentration of 5 - 20 µg/ml. |
WB
Use a concentration of 0.2 - 2 µg/ml. |
ターゲット情報
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機能
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. -
関連疾患
Defects in TNNI3 are the cause of cardiomyopathy familial hypertrophic type 7 (CMH7) [MIM:613690]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
Defects in TNNI3 are the cause of cardiomyopathy familial restrictive type 1 (RCM1) [MIM:115210]. RCM1 is an heart muscle disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
Defects in TNNI3 are the cause of cardiomyopathy dilated type 2A (CMD2A) [MIM:611880]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Defects in TNNI3 are the cause of cardiomyopathy dilated type 1FF (CMD1FF) [MIM:613286]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. -
配列類似性
Belongs to the troponin I family. - Information by UniProt
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参照データベース
- Entrez Gene: 493744 Cat
- Entrez Gene: 511094 Cow
- Entrez Gene: 403566 Dog
- Entrez Gene: 100034065 Horse
- Entrez Gene: 7137 Human
- Entrez Gene: 21954 Mouse
- Entrez Gene: 100049696 Pig
- Entrez Gene: 29248 Rat
see all -
別名
- cardiac muscle antibody
- Cardiac troponin I antibody
- cardiomyopathy, dilated 2A (autosomal recessive) antibody
see all
画像
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Formalin-fixed, paraffin-embedded pig heart tissue stained for Cardiac Troponin I with ab231064 at 20 μg/ml in immunohistochemical analysis. DAB staining.
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Anti-Cardiac Troponin I antibody (ab231064) at 2 µg/ml + Mouse skeletal muscle lysate
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Anti-Cardiac Troponin I antibody (ab231064) at 2 µg/ml + Pig skeletal muscle lysate
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Anti-Cardiac Troponin I antibody (ab231064) at 2 mg/ml + Pig heart lysate
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Anti-Cardiac Troponin I antibody (ab231064) at 2 µg/ml + Mouse heart lysate
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Anti-Cardiac Troponin I antibody (ab231064) at 2 µg/ml + Recombinant pig Cardiac Troponin I
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Formalin-fixed, paraffin-embedded pig tongue tissue stained for Cardiac Troponin I with ab231064 at 20 μg/ml in immunohistochemical analysis. DAB staining.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab231064 は論文での使用が確認できていません。