Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6685(B)] to CaMKII
- Suitable for: WB, Flow Cyt
- Reacts with: Mouse, Rat, Human
製品名Anti-CaMKII antibody [EPR6685(B)]
CaMKII 一次抗体 製品一覧
製品の詳細Rabbit monoclonal [EPR6685(B)] to CaMKII
アプリケーション適用あり: WB, Flow Cytmore details
適用なし: ICC/IF,IHC-P or IP
種交差性交差種: Mouse, Rat, Human
A synthetic peptide, corresponding to residues in Human CaMKII (UniProt Q13554).
- Human pancreas, fetal kidney, HeLa, Jurkat, SH SY5Y, BxPC3 and C6 lysates; Permeabilized C6 cells.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
解離定数（KD 値）KD = 2.60 x 10 -11 M Learn more about KD
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
精製度Tissue culture supernatant
Our Abpromise guarantee covers the use of ab126789 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Detects a band of approximately 45-70 kDa (predicted molecular weight: 51-73 kDa).|
|Flow Cyt||1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
機能CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Contains 1 protein kinase domain.
細胞内局在Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse. Postsynaptic lipid rafts.
- Information by UniProt
- Calcium/calmodulin dependent protein kinase II alpha antibody
- Calcium/calmodulin dependent protein kinase II beta antibody
- Calcium/calmodulin dependent protein kinase II delta antibody
All lanes : Anti-CaMKII antibody [EPR6685(B)] (ab126789) at 1/1000 dilution
Lane 1 : Human pancreas lysate
Lane 2 : Human fetal kidney lysate
Lane 3 : HeLa lysate
Lane 4 : Jurkat lysate
Lane 5 : SH SY5Y lysate
Lane 6 : BxPC3 lysate
Lane 7 : C6 lysate
Lysates/proteins at 10 µg per lane.
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 51-73 kDa
ab126789 at 1/10 dilution staining CaMKII in permeabilized C6 cells by Flow cytometry (red) compared with a rabbit IgG negative control (green).
Equilibrium disassociation constant (KD)
Learn more about KD
Click here to learn more about KD