製品の概要

  • 製品名

    Calpeptin, cell-permeable calpain inhibitor
  • 製品の詳細

    Potent, cell-permeable calpain inhibitor
  • 生理活性の詳細

    Potent, cell-permeable calpain inhibitor, a Ca2+-dependent protease. Ki values are 34 and 52 nM for μ- and m-calpains, respectively. Demonstrates neuroprotective effects suggesting ability to cross the blood-brain barrier.
  • 精製度

    > 98%
  • CAS 番号

    117591-20-5
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Smith AW  et al. Calpain inhibition attenuates apoptosis of retinal ganglion cells in acute optic neuritis. Invest Ophthalmol Vis Sci 52:4935-41 (2011). Read more (PubMed: 21613375) »
  • Rodríguez-Agudo D  et al. Rat histidine decarboxylase is a substrate for m-calpain in vitro. Biochem Biophys Res Commun 271:777-81 (2000). Read more (PubMed: 10814538) »
  • Tsujinaka T  et al. Synthesis of a new cell penetrating calpain inhibitor (calpeptin). Biochem Biophys Res Commun 153:1201-8 (1988). Read more (PubMed: 2839170) »
See all 4 Publications for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab120804.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

登録