Anti-CAB3 抗体 (ab16717)
Key features and details
- Rabbit polyclonal to CAB3
- Suitable for: IP, ICC/IF, WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-CAB3 antibody -
製品の詳細
Rabbit polyclonal to CAB3 -
由来種
Rabbit -
特異性
This antibody recognises the beta 3 calcium channel subunit. -
アプリケーション
適用あり: IP, ICC/IF, WBmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide corresponding to CAB3 aa 1-15 conjugated to keyhole limpet haemocyanin.
Sequence:MYDDSYVPGFEDSEA
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ポジティブ･コントロール
- Rat cortical and hippocampal, neuronal membranes. Negative control: non neuronal cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Ammonium Sulphate Precipitation -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab16717の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
|
|
| ICC/IF |
Use at an assay dependent concentration.
|
|
| WB | (1) |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
IP
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. -
組織特異性
Expressed mostly in brain, smooth muscle and ovary. -
配列類似性
Belongs to the calcium channel beta subunit family.
Contains 1 SH3 domain. - Information by UniProt
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参照データベース
- Entrez Gene: 25297 Rat
- SwissProt: P54287 Rat
- Unigene: 2808 Rat
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別名
- CAB3 antibody
- CACB3_HUMAN antibody
- Cacnb3 antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab16717 は 1 報の論文で使用されています。
- Uriu Y et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285:21750-67 (2010). WB ; Human . PubMed: 20452978
