製品の概要

  • 製品名

    Buspirone hydrochloride, 5-HT1A agonist
  • 製品の詳細

    5-HT1A agonist. Anxiolytic.
  • 生理活性の詳細

    5-HT1A partial agonist (Ki = 9.3 - 29.5 nM). Anxiolytic in vivo. Many reported effects including actions on dopaminergic and noradrenergic pathways, as well as the GABA-benzodiazepine receptor chloride ionophore complex.
  • 精製度

    > 99%
  • CAS 番号

    33386-08-2
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Jahanshahi A  et al. Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats. Neurosci Lett 473:136-40 (2010). Read more (PubMed: 20178829) »
  • Eison AS & Temple DL Buspirone: review of its pharmacology and current perspectives on its mechanism of action. Am J Med 80:1-9 (1986). Read more (PubMed: 2870639) »
  • Skolnick P  et al. Preclinical pharmacology of buspirone hydrochloride. Pharmacotherapy 4:308-14 (0). Read more (PubMed: 6151169) »

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