Bromocriptine mesylate, D2-like dopamine receptor agonist (ab120574)
Key features and details
- Potent, selective D2-like dopamine receptor agonist
- CAS Number: 22260-51-1
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM (with heating)
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Bromocriptine mesylate, D2-like dopamine receptor agonist -
製品の詳細
Potent, selective D2-like dopamine receptor agonist -
生理活性の詳細
Potent, selective D2-like dopamine receptor agonist (Ki values are ~8 (D2), ~5 (D3), ~290 (D4), ~440 (D1) and ~450 nM (D5)). Inhibits the release of pituitary prolactin and stimulates motor activity in Parkinson's disease. Also reverses glutamate transporter 1 (GLT-1) activity, increasing glutamate levels.
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精製度
> 99% -
CAS 番号
22260-51-1 -
構造式
製品の特性
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体系名
(5a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione methanesulfonate -
分子量
750.70 -
分子式
C32H40BrN5O5.CH3SO3H -
PubChem 登録番号
31100 -
保存方法
Store at +4°C. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM and in ethanol to 25 mM (with heating) -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CS(=O)(=O)O.Brc3nc2cccc1C4=C[C@H](CN(C)[C@@H]4Cc3c12)C(=O)N[C@@]7(O[C@]6(O)N([C@@H](CC(C)C)C(=O)N5CCC[C@H]56)C7=O)C(C)C -
由来
Synthetic
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研究分野
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120574 は 1 報の論文で使用されています。
- Ji M et al. An Antiviral Peptide from Alopecosa nagpag Spider Targets NS2B-NS3 Protease of Flaviviruses. Toxins (Basel) 11:N/A (2019). PubMed: 31658707