Key features and details
- Goat polyclonal to BRD2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
BRD2 一次抗体 製品一覧
製品の詳細Goat polyclonal to BRD2
アプリケーション適用あり: WBmore details
交差が予測される動物種: Mouse, Cow, Rhesus monkey, Gorilla
Synthetic peptide (Human) - which represented a portion of human Bromodomain Containing 2 (BRD 2) between the putative nuclear localization signal and the ET domain.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris
Concentration information loading...
精製度Immunogen affinity purified
- Cell Biology
- Proteolysis / Ubiquitin
- Proteasome / Ubiquitin
- Ubiquitin E3 Enzymes
- RING Finger E3 Ligase
Our Abpromise guarantee covers the use of ab3718 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/10000 - 1/40000. Predicted molecular weight: 110 kDa.|
機能May play a role in spermatogenesis or folliculogenesis.
配列類似性Contains 2 bromo domains.
Contains 1 ET domain.
ドメインOne bromodomain is sufficient for a partial interaction with histone H4 acetylated at 'Lys-13'.
- Information by UniProt
- BRD 2 antibody
- Brd2 antibody
- BRD2_HUMAN antibody
Sample: Hela cell total RIPA extract (10
Antibody: Affinity purified Goat anti-BRD 2 (ab3718) (diluted 1 / 20,000)
CIP: Calf Intestinal Phosphatase
Detection: ECL exposed for 1 minute.
ab3718 は 5 報の論文で使用されています。
- Sun Y et al. BET protein inhibition mitigates acute myocardial infarction damage in rats via the TLR4/TRAF6/NF-?B pathway. Exp Ther Med 10:2319-2324 (2015). WB . PubMed: 26668635
- Dhar S et al. Insights into role of bromodomain, testis-specific (Brdt) in acetylated histone H4-dependent chromatin remodeling in mammalian spermiogenesis. J Biol Chem 287:6387-405 (2012). ICC/IF ; Rat . PubMed: 22215678
- Draker R et al. A combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activation. PLoS Genet 8:e1003047 (2012). WB . PubMed: 23144632
- Lin A et al. The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4. J Virol 82:12009-19 (2008). WB ; Human . PubMed: 18922874
- Benevolenskaya EV et al. Binding of pRB to the PHD protein RBP2 promotes cellular differentiation. Mol Cell 18:623-35 (2005). PubMed: 15949438