Key features and details
- Goat polyclonal to BRD2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
BRD2 一次抗体 製品一覧
製品の詳細Goat polyclonal to BRD2
アプリケーション適用あり: WBmore details
交差が予測される動物種: Mouse, Cow, Rhesus monkey, Gorilla
Synthetic peptide (Human) - which represented a portion of human Bromodomain Containing 2 (BRD 2) between the putative nuclear localization signal and the ET domain.
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris
Concentration information loading...
精製度Immunogen affinity purified
- Cell Biology
- Proteolysis / Ubiquitin
- Proteasome / Ubiquitin
- Ubiquitin E3 Enzymes
- RING Finger E3 Ligase
Our Abpromise guarantee covers the use of ab3718 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/10000 - 1/40000. Predicted molecular weight: 110 kDa.|
機能May play a role in spermatogenesis or folliculogenesis.
配列類似性Contains 2 bromo domains.
Contains 1 ET domain.
ドメインOne bromodomain is sufficient for a partial interaction with histone H4 acetylated at 'Lys-13'.
- Information by UniProt
- BRD 2 antibody
- Brd2 antibody
- BRD2_HUMAN antibody
Sample: Hela cell total RIPA extract (10
Antibody: Affinity purified Goat anti-BRD 2 (ab3718) (diluted 1 / 20,000)
CIP: Calf Intestinal Phosphatase
Detection: ECL exposed for 1 minute.
ab3718 は 6 報の論文で使用されています。
- Khan KA et al. The Use of Mononucleosome Immunoprecipitation for Analysis of Combinatorial Histone Post-translational Modifications and Purification of Nucleosome-Interacting Proteins. Front Cell Dev Biol 8:331 (2020). PubMed: 32457909
- Sun Y et al. BET protein inhibition mitigates acute myocardial infarction damage in rats via the TLR4/TRAF6/NF-?B pathway. Exp Ther Med 10:2319-2324 (2015). WB . PubMed: 26668635
- Dhar S et al. Insights into role of bromodomain, testis-specific (Brdt) in acetylated histone H4-dependent chromatin remodeling in mammalian spermiogenesis. J Biol Chem 287:6387-405 (2012). ICC/IF ; Rat . PubMed: 22215678
- Draker R et al. A combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activation. PLoS Genet 8:e1003047 (2012). WB . PubMed: 23144632
- Lin A et al. The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4. J Virol 82:12009-19 (2008). WB ; Human . PubMed: 18922874
- Benevolenskaya EV et al. Binding of pRB to the PHD protein RBP2 promotes cellular differentiation. Mol Cell 18:623-35 (2005). PubMed: 15949438