Anti-BPOZ/ABTB1 抗体 (ab1077)
Key features and details
- Goat polyclonal to BPOZ/ABTB1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-BPOZ/ABTB1 antibody -
製品の詳細
Goat polyclonal to BPOZ/ABTB1 -
由来種
Goat -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Dog
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免疫原
Synthetic peptide corresponding to Human BPOZ/ABTB1 aa 323-336 (N terminal).
Sequence:RALEDLLVSIGLDC
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ポジティブ･コントロール
- WB: Human heart tissue lysate. IHC-P: Human heart and brain (cerebellum) tissues.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab1077の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa).
1 hour primary incubation is recommended for this product. |
|
| IHC-P |
Use a concentration of 3.75 mg/ml.
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa). 1 hour primary incubation is recommended for this product. |
|
IHC-P
Use a concentration of 3.75 mg/ml. |
ターゲット情報
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機能
May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. -
組織特異性
Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart. -
配列類似性
Contains 2 ANK repeats.
Contains 2 BTB (POZ) domains. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 80325 Human
- Entrez Gene: 80283 Mouse
- Entrez Gene: 297432 Rat
- Omim: 608308 Human
- SwissProt: Q969K4 Human
- SwissProt: Q99LJ2 Mouse
- SwissProt: Q5XIU1 Rat
- Unigene: 107812 Human
see all -
別名
- ABTB 1 antibody
- Abtb1 antibody
- ABTB1_HUMAN antibody
see all
画像
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Western blot - Anti-BPOZ/ABTB1 antibody (ab1077)Anti-BPOZ/ABTB1 antibody (ab1077) at 1 µg/ml + Human heart tissue lysate (RIPA buffer, 35µg total protein per lane)
Predicted band size: 39 kDaPrimary incubated for 1 hour.
Detected by western blot using chemiluminescence.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab1077 は 1 報の論文で使用されています。
- Roy A & Pahan K Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: Implications for Parkinson's disease. FEBS Lett 587:3567-74 (2013). ICC/IF ; Mouse . PubMed: 24076025