Anti-BOTOX 抗体 [230F9] (ab40786)
Key features and details
- Mouse monoclonal [230F9] to BOTOX
- Suitable for: ICC/IF, Inhibition Assay
- Reacts with: Species independent
- Isotype: IgG
製品の概要
-
製品名
Anti-BOTOX antibody [230F9]
BOTOX 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [230F9] to BOTOX -
由来種
Mouse -
特異性
BoTox-A (1280-1292) 100%; BoTox-A 100% Does not cross react with BoTox-B, BoTox-C, BoTox-E or BoTox-F (1272-1280) -
アプリケーション
適用あり: ICC/IF, Inhibition Assaymore details -
種交差性
交差種: Species independent -
免疫原
Synthetic peptide corresponding to BOTOX (C terminal).
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Constituent: Tissue culture supernatant -
Concentration information loading...
-
精製度
Tissue culture supernatant -
特記事項(精製)
Sterile filtered culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
230F9 -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab40786の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ICC/IF |
Use at an assay dependent concentration.
|
|
Inhibition Assay |
Use at an assay dependent concentration.
Inhibits BoTox-A binding to Neuro2A cells treated with GT1b ganglioside which can be eliminated by prior incubation with synthetic peptide immunogen. |
特記事項 |
---|
ICC/IF
Use at an assay dependent concentration. |
Inhibition Assay
Use at an assay dependent concentration. Inhibits BoTox-A binding to Neuro2A cells treated with GT1b ganglioside which can be eliminated by prior incubation with synthetic peptide immunogen. |
ターゲット情報
-
関連性
Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25. -
別名
- Atx antibody
- BotA antibody
- BOTOX antibody
see all
データシートおよび資料
-
Datasheet download
参考文献 (1)
ab40786 は 1 報の論文で使用されています。
- Bräuer L et al. Staphylococcus aureus and Pseudomonas aeruginosa express and secrete human surfactant proteins. PLoS One 8:e53705 (2013). PubMed: 23349731