Anti-Blood Group A, B and H Antigens 抗体 [HE-10] (ab2523)

Submit a review Q&A (1)References (2)

Key features and details

  • Mouse monoclonal [HE-10] to Blood Group A, B and H Antigens
  • Suitable for: Agglutination, IHC-P
  • Reacts with: Human
  • Isotype: IgM

製品の概要

  • 製品名

    Anti-Blood Group A, B and H Antigens antibody [HE-10]

  • 製品の詳細

    Mouse monoclonal [HE-10] to Blood Group A, B and H Antigens

  • 由来種

    Mouse

  • 特異性

    Studies with specific oligosaccharides showed that this antibody detects A and H antigens with chain types 3 and 4. This antibody does not react with A disaccharide, A trisaccharide, A type 1, A type 2 or ALe b. This antibody reacts with normal and malignant tissue sections from donors with blood group A. It does not react with normal tissue sections from donors with blood group B and 0 but it does react specifically with malignant tissues.

  • アプリケーション

    適用あり: Agglutination, IHC-Pmore details

  • 種交差性

    交差種: Human

  • 免疫原

    Mixture of erythrocytes of blood group A1 and glycoprotein fraction isolated from the saliva of secretors with blood group A.

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • バッファー

    Constituent: Tissue culture supernatant
  • Concentration information loading...

  • 精製度

    Tissue culture supernatant

  • 特記事項（精製）

    Concentrated by ultrafiltration (100 kDa cut-off). Actual immunoglobulin concentration not determined.

  • ポリ/モノ

    モノクローナル

  • クローン名

    HE-10

  • ミエローマ

    unknown

  • アイソタイプ

    IgM

  • 軽鎖の種類

    unknown

  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab2523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Agglutination Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

This antibody is excellent as a tumour marker in patients of blood group B and 0.

参考文献

ab2523 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab2523 は 2 報の論文で使用されています。

  • Vanak J  et al. Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities. Neoplasma 36:479-88 (1989). PubMed: 2475797
  • Nemec M  et al. Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine. Vox Sang 52:125-8 (1987). PubMed: 2440181

レビューと Q&A

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Question

Which strain of mouse with this ab react with?

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Answer

I have talked to the lab about ab2523 and it seems as though the antibody will not react with mouse tissue. The mouse species was added by mistake to the datasheet. Please accept my apologies for this mistake and if you purchased the antibody to specifically use it on mouse tissue then I would be happy to either help find a replacement antibody or to process a refund.

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