Anti-Blood Group A, B and H Antigens 抗体 [HE-10] (ab2523)

Submit a review Q&A (1)References (2)

Key features and details

  • Mouse monoclonal [HE-10] to Blood Group A, B and H Antigens
  • Reacts with: Human
  • Isotype: IgM

製品の概要

  • 製品名

    Anti-Blood Group A, B and H Antigens antibody [HE-10]

  • 製品の詳細

    Mouse monoclonal [HE-10] to Blood Group A, B and H Antigens

  • 由来種

    Mouse

  • 特異性

    Studies with specific oligosaccharides showed that this antibody detects A and H antigens with chain types 3 and 4. This antibody does not react with A disaccharide, A trisaccharide, A type 1, A type 2 or ALe b. This antibody reacts with normal and malignant tissue sections from donors with blood group A. It does not react with normal tissue sections from donors with blood group B and 0 but it does react specifically with malignant tissues.

  • 種交差性

    交差種: Human

  • 免疫原

    Mixture of erythrocytes of blood group A1 and glycoprotein fraction isolated from the saliva of secretors with blood group A.

  • 特記事項

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • バッファー

    Constituent: Tissue culture supernatant
  • Concentration information loading...

  • 精製度

    Tissue culture supernatant

  • 特記事項（精製）

    Concentrated by ultrafiltration (100 kDa cut-off). Actual immunoglobulin concentration not determined.

  • ポリ/モノ

    モノクローナル

  • クローン名

    HE-10

  • ミエローマ

    unknown

  • アイソタイプ

    IgM

  • 軽鎖の種類

    unknown

  • 研究分野

参考文献 (2)

ab2523 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab2523 は 2 報の論文で使用されています。

  • Vanak J  et al. Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities. Neoplasma 36:479-88 (1989). PubMed: 2475797
  • Nemec M  et al. Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine. Vox Sang 52:125-8 (1987). PubMed: 2440181

レビューと Q&A

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Question

Which strain of mouse with this ab react with?

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Answer

I have talked to the lab about ab2523 and it seems as though the antibody will not react with mouse tissue. The mouse species was added by mistake to the datasheet. Please accept my apologies for this mistake and if you purchased the antibody to specifically use it on mouse tissue then I would be happy to either help find a replacement antibody or to process a refund.

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