Anti-Blood Group A, B and H Antigens 抗体 [HE-10] (ab2523)

Submit a review Q&A (1)References (2)
Flow Cytometry - Anti-Blood Group A, B and H Antigens antibody [HE-10] (ab2523)
  • Flow Cytometry - Anti-Blood Group A, B and H Antigens antibody [HE-10] (ab2523)

Key features and details

  • Mouse monoclonal [HE-10] to Blood Group A, B and H Antigens
  • Suitable for: Flow Cyt
  • Reacts with: Human
  • Isotype: IgM

製品の概要

  • 製品名

    Anti-Blood Group A, B and H Antigens antibody [HE-10]

  • 製品の詳細

    Mouse monoclonal [HE-10] to Blood Group A, B and H Antigens

  • 由来種

    Mouse

  • 特異性

    Studies with specific oligosaccharides showed that this antibody detects A and H antigens with chain types 3 and 4. This antibody does not react with A disaccharide, A trisaccharide, A type 1, A type 2 or ALe b. This antibody reacts with normal and malignant tissue sections from donors with blood group A. It does not react with normal tissue sections from donors with blood group B and 0 but it does react specifically with malignant tissues.

  • アプリケーション

    適用あり: Flow Cytmore details

  • 種交差性

    交差種: Human

  • 免疫原

    Tissue, cells or virus corresponding to Blood Group A, B and H Antigens. Mixture of erythrocytes of blood group A1 and glycoprotein fraction isolated from the saliva of secretors with blood group A.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • バッファー

    Constituent: Tissue culture supernatant
  • Concentration information loading...

  • 精製度

    Tissue culture supernatant

  • 特記事項（精製）

    Concentrated by ultrafiltration (100 kDa cut-off). Actual immunoglobulin concentration not determined.

  • ポリ/モノ

    モノクローナル

  • クローン名

    HE-10

  • ミエローマ

    unknown

  • アイソタイプ

    IgM

  • 軽鎖の種類

    unknown

  • 研究分野

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab2523の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
Flow Cyt
Use at an assay dependent concentration.
特記事項
Flow Cyt
Use at an assay dependent concentration.

画像

  • Flow Cytometry - Anti-Blood Group A, B and H Antigens antibody [HE-10] (ab2523)
    Flow Cytometry - Anti-Blood Group A, B and H Antigens antibody [HE-10] (ab2523)

    Separation of human erythrocytes from blood group A donor (red-filled) from erythrocytes from blood group 0 donor (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood samples using ab2523.

  • Flow Cytometry - Anti-Blood Group A, B and H Antigens antibody [HE-10] (ab2523)
    Flow Cytometry - Anti-Blood Group A, B and H Antigens antibody [HE-10] (ab2523)

    Flow cytometry surface staining pattern of human peripheral whole blood from group A donor stained using ab2523.

参考文献 (2)

ab2523 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab2523 は 2 報の論文で使用されています。

  • Vanak J  et al. Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities. Neoplasma 36:479-88 (1989). PubMed: 2475797
  • Nemec M  et al. Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine. Vox Sang 52:125-8 (1987). PubMed: 2440181

レビューと Q&A

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レビューを送る 質問を送る

Question

Which strain of mouse with this ab react with?

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Answer

I have talked to the lab about ab2523 and it seems as though the antibody will not react with mouse tissue. The mouse species was added by mistake to the datasheet. Please accept my apologies for this mistake and if you purchased the antibody to specifically use it on mouse tissue then I would be happy to either help find a replacement antibody or to process a refund.

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