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Lamin ~ 注目ターゲットのおすすめ製品


ウサギ・モノクローナル 抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Lamin A + C HuFlow Cyt, ICC/IF, IHC-P, IP, WB103 ab108595
Lamin A + C Ms, Rat, Hu, S triICC/IF, IHC-P, IP, WB24 ab108922
Lamin A + C(HRP) HuIHC-P, WB ab193904
Lamin B1 Hu, Ms, RatICC/IF, IHC-P, IP, WB93 ab133741
Lamin B1 (HRP) HuIHC-P, WB ab194109
Lamin B1
Alexa Fluor® 488
HuICC/IF ab194106
Lamin B1
Alexa Fluor® 647
Ms, Rat, HuICC/IF ab194108
Lamin B2Hu, Ms, RatICC/IF, IHC-P, IP, WB51 ab151735

抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Lamin ARb-P
Hu, Ms, RatICC/IF, IHC-P, WB1517ab26300
Lamin AMs-M Ms, Rat, Cow, Dog, Hu, MkFlow Cyt, ICC, ICC/IF, IHC-Fr, IHC-P, WB2517 ab8980
Lamin A + CMs-M Ms, Rat, Shp, Hm, Cow, Dog, HuFlow Cyt, ICC, ICC/IF, IHC-Fr, IP, WB1712 ab8984
Lamin A + CMs-MHu, AGMkFlow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB175 ab40567
Lamin A + C (HRP)Ms-M Hu, AGMkIHC-P, IP, WB11 ab196636
Lamin B1Rb-P
Ms, Rat, Hu, Xl, InMtj, PigICC/IF, IHC - Wmt, IHC-Fr, IHC-P, WB20882 ab16048
Lamin B2Ms-MHu, Ms, Hm, Xl, ZfshFlow Cyt, ICC, IHC-Fr, IP, WB165 ab8983
pan LaminMs-MHu, Ms, Cow, Kg, Rtrout, XlICC/IF, WB32 ab20740
抗体一覧

タンパク質・ペプチド

製品名

由来

適用・アプリケーション

製品番号

Lamin A protein (Recombinant)HuSDS-PAGE, WBab83472
Lamin B1 protein (Recombinant)HuELISA, SDS-PAGE, WBab114163
Lamin B1 peptideMsBLab16375
Lamin A peptideHuab27812
タンパク質・ペプチド一覧

Lamin について

Lamin A
Function
機能
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
Sequence similarities
配列類似性
  • Belongs to the intermediate filament family.
Cellular localization
細胞内局在性
Nucleus. Nucleus envelope. Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleaveage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C.

Lamin B1
Function
機能
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Sequence similarities
配列類似性
  • Belongs to the intermediate filament family.
Cellular localization
細胞内局在性
Nucleus inner membrane.

Lamin B2
Function
機能
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Sequence similarities
配列類似性
  • Belongs to the intermediate filament family.
Cellular localization
細胞内局在性
Nucleus inner membrane.

Lamin A+C
Function
機能
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
Sequence similarities
配列類似性
  • Belongs to the intermediate filament family.
Cellular localization
細胞内局在性
Nucleus. Nucleus envelope. Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleaveage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C.

関連リンク


注目ターゲット

ローディング・コントロール抗体
サンプル・セット

ローディング・コントロール抗体の
ススメ

ローディング・コントロール・
ガイド


Alexa Fluor® is a registered trademark of Life Technologies. Alexa Fluor® dye conjugates contain(s) technology licensed to Abcam by Life Technologies.


ウサギ・モノクローナル 抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Lamin A + C HuFlow Cyt, ICC/IF, IHC-P, IP, WB103 ab108595
Lamin A + C Ms, Rat, Hu, S triICC/IF, IHC-P, IP, WB24 ab108922
Lamin A + C(HRP) HuIHC-P, WB ab193904
Lamin B1 Hu, Ms, RatICC/IF, IHC-P, IP, WB93 ab133741
Lamin B1 (HRP) HuIHC-P, WB ab194109
Lamin B1
Alexa Fluor® 488
HuICC/IF ab194106
Lamin B1
Alexa Fluor® 647
Ms, Rat, HuICC/IF ab194108
Lamin B2Hu, Ms, RatICC/IF, IHC-P, IP, WB51 ab151735

抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Lamin ARb-P
Hu, Ms, RatICC/IF, IHC-P, WB1517ab26300
Lamin AMs-M Ms, Rat, Cow, Dog, Hu, MkFlow Cyt, ICC, ICC/IF, IHC-Fr, IHC-P, WB2517 ab8980
Lamin A + CMs-M Ms, Rat, Shp, Hm, Cow, Dog, HuFlow Cyt, ICC, ICC/IF, IHC-Fr, IP, WB1712 ab8984
Lamin A + CMs-MHu, AGMkFlow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB175 ab40567
Lamin A + C (HRP)Ms-M Hu, AGMkIHC-P, IP, WB11 ab196636
Lamin B1Rb-P
Ms, Rat, Hu, Xl, InMtj, PigICC/IF, IHC - Wmt, IHC-Fr, IHC-P, WB20882 ab16048
Lamin B2Ms-MHu, Ms, Hm, Xl, ZfshFlow Cyt, ICC, IHC-Fr, IP, WB165 ab8983
pan LaminMs-MHu, Ms, Cow, Kg, Rtrout, XlICC/IF, WB32 ab20740
抗体一覧

タンパク質・ペプチド

製品名

由来

適用・アプリケーション

製品番号

Lamin A protein (Recombinant)HuSDS-PAGE, WBab83472
Lamin B1 protein (Recombinant)HuELISA, SDS-PAGE, WBab114163
Lamin B1 peptideMsBLab16375
Lamin A peptideHuab27812
タンパク質・ペプチド一覧

Lamin について

Lamin A
Function
機能
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
Sequence similarities
配列類似性
  • Belongs to the intermediate filament family.
Cellular localization
細胞内局在性
Nucleus. Nucleus envelope. Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleaveage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C.

Lamin B1
Function
機能
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Sequence similarities
配列類似性
  • Belongs to the intermediate filament family.
Cellular localization
細胞内局在性
Nucleus inner membrane.

Lamin B2
Function
機能
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Sequence similarities
配列類似性
  • Belongs to the intermediate filament family.
Cellular localization
細胞内局在性
Nucleus inner membrane.

Lamin A+C
Function
機能
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
Sequence similarities
配列類似性
  • Belongs to the intermediate filament family.
Cellular localization
細胞内局在性
Nucleus. Nucleus envelope. Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleaveage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C.

関連リンク


注目ターゲット

ローディング・コントロール抗体
サンプル・セット

ローディング・コントロール抗体の
ススメ

ローディング・コントロール・
ガイド


Alexa Fluor® is a registered trademark of Life Technologies. Alexa Fluor® dye conjugates contain(s) technology licensed to Abcam by Life Technologies.

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