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CD31 ~ 注目ターゲットのおすすめ製品


ウサギ・モノクローナル 抗体

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数 評価

製品番号

CD31 HuFlow Cyt, IHC-P, IP, WB129ab76533
CD31 HuFlow Cyt, IHC-P, WB53 ab134168
CD31 (pY713) HuFlow Cyt, ICC/IF, WB1 ab180175
CD31 Ms, RatIP, WB ab213175
CD31
BSA and Azide free
HuIHC-P, WB5ab207090
CD31
Low endotoxin, Azide free
HuFlow Cyt, IHC-P, WB3ab216459
CD31 Alexa Fluor® 647 Hu ab218582

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数 評価

製品番号

CD31Rb-P Ms, Hu, PigICC/IF, IHC-FoFr, IHC-Fr, IHC-P, WB49298 ab28364
CD31Ms-M Ms, HuICC/IF, IHC - Wmt, IP, WB4336 ab24590
CD31Ms-M Rb, Hu, CynMk, MsFlow Cyt, ICC/IF, IHC-Fr, IHC-P, WB3819ab9498
CD31Rb-P HuFlow Cyt, ICC/IF, IHC-Fr, IHC-P, WB158 ab32457
CD31Ms-M Hu, Cow, RatBL, ELISA, Flow Cyt, GSA, ICC, ICC/IF, IHC-Fr, IP134ab119339
CD31Rat-MMsICC/IF, IHC-Fr, IHC-P257 ab56299
CD31Rat-M MsFlow Cyt, ICC/IF, IHC-Fr, IP516 ab7388
CD31Hm-M Ms, Hu, Hm, NHuPrmBL, ELISA, Flow Cyt, ICC, IHC, IP, Neut41 ab119341
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タンパク質・ペプチド

製品名

由来

適用・アプリケーション

製品番号

CD31 protein (Recombinant)HuELISA, SDS-PAGE, WBab131797
CD31 protein (Active)(Recombinant)HuFuncS, SDS-PAGEab155607
CD31 protein(Recombinant)HuHPLC, SDS-PAGEab129040
タンパク質・ペプチド一覧

キット

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容量

製品番号

CD31 ELISA Kit Hu1x96testsab190814
CD31 ELISA Kit Ms1x96testsab204527
CD31 ELISA Kit Hu10x96testsab209893
CD31 Matched Antibody Pair Kit Ms10x96testsab212065
キット一覧

CD31 について

Function
機能
Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).
Tissue specificity
組織特異性
Expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells. Isoform Long predominates in all tissues examined. Isoform Delta12 is detected only in trachea. Isoform Delta14-15 is only detected in lung. Isoform Delta14 is detected in all tissues examined with the strongest expression in heart. Isoform Delta15 is expressed in brain, testis, ovary, cell surface of platelets, human umbilical vein endothelial cells (HUVECs), Jurkat T-cell leukemia, human erythroleukemia (HEL) and U937 histiocytic lymphoma cell lines (at protein level).
Sequence similarities
配列類似性
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
Post-translational modifications
翻訳後修飾
Phosphorylated on Ser and Tyr residues after cellular activation. In endothelial cells Fyn mediates mechanical-force (stretch or pull) induced tyrosine phosphorylation.
Cellular localization
細胞内局在性
Membrane. Cell junction. Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells and Cell junction. Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells.

関連リンク


Immunology
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注目
ターゲット

内皮細胞マーカー抗体

よりよい CD31 抗体を

ヒト CD 抗原チャート


ウサギ・モノクローナル 抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

CD31 HuFlow Cyt, IHC-P, IP, WB129ab76533
CD31 HuFlow Cyt, IHC-P, WB53 ab134168
CD31 (pY713) HuFlow Cyt, ICC/IF, WB1 ab180175
CD31 Ms, RatIP, WB ab213175
CD31
BSA and Azide free
HuIHC-P, WB5ab207090
CD31
Low endotoxin, Azide free
HuFlow Cyt, IHC-P, WB3ab216459
CD31 Alexa Fluor® 647 Hu ab218582

抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

CD31Rb-P Ms, Hu, PigICC/IF, IHC-FoFr, IHC-Fr, IHC-P, WB49298 ab28364
CD31Ms-M Ms, HuICC/IF, IHC - Wmt, IP, WB4336 ab24590
CD31Ms-M Rb, Hu, CynMk, MsFlow Cyt, ICC/IF, IHC-Fr, IHC-P, WB3819ab9498
CD31Rb-P HuFlow Cyt, ICC/IF, IHC-Fr, IHC-P, WB158 ab32457
CD31Ms-M Hu, Cow, RatBL, ELISA, Flow Cyt, GSA, ICC, ICC/IF, IHC-Fr, IP134ab119339
CD31Rat-MMsICC/IF, IHC-Fr, IHC-P257 ab56299
CD31Rat-M MsFlow Cyt, ICC/IF, IHC-Fr, IP516 ab7388
CD31Hm-M Ms, Hu, Hm, NHuPrmBL, ELISA, Flow Cyt, ICC, IHC, IP, Neut41 ab119341
抗体一覧

タンパク質・ペプチド

製品名

由来

適用・アプリケーション

製品番号

CD31 protein (Recombinant)HuELISA, SDS-PAGE, WBab131797
CD31 protein (Active)(Recombinant)HuFuncS, SDS-PAGEab155607
CD31 protein(Recombinant)HuHPLC, SDS-PAGEab129040
タンパク質・ペプチド一覧

キット

製品名

交差種

容量

製品番号

CD31 ELISA Kit Hu1x96testsab190814
CD31 ELISA Kit Ms1x96testsab204527
CD31 ELISA Kit Hu10x96testsab209893
CD31 Matched Antibody Pair Kit Ms10x96testsab212065
キット一覧

CD31 について

Function
機能
Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).
Tissue specificity
組織特異性
Expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells. Isoform Long predominates in all tissues examined. Isoform Delta12 is detected only in trachea. Isoform Delta14-15 is only detected in lung. Isoform Delta14 is detected in all tissues examined with the strongest expression in heart. Isoform Delta15 is expressed in brain, testis, ovary, cell surface of platelets, human umbilical vein endothelial cells (HUVECs), Jurkat T-cell leukemia, human erythroleukemia (HEL) and U937 histiocytic lymphoma cell lines (at protein level).
Sequence similarities
配列類似性
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
Post-translational modifications
翻訳後修飾
Phosphorylated on Ser and Tyr residues after cellular activation. In endothelial cells Fyn mediates mechanical-force (stretch or pull) induced tyrosine phosphorylation.
Cellular localization
細胞内局在性
Membrane. Cell junction. Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells and Cell junction. Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells.

関連リンク


Immunology
ポータル

注目
ターゲット

内皮細胞マーカー抗体

よりよい CD31 抗体を

ヒト CD 抗原チャート

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